DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1607 and SLC7A7

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001119577.1	Gene:	SLC7A7 / 9056	HGNCID:	11065	Length:	511	Species:	Homo sapiens

Alignment Length:	468	Identity:	222/468 - (47%)
Similarity:	332/468 - (70%)	Gaps:	4/468 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 GDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMV 97
            |||...|..:|.||.::|||||..:|||::|||||||||.|||:|:.|..|:|::|.:.||||:.
Human    21 GDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVF 85

  Fly    98 GAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPE 162
            ||.|||||||.|.||||.||||:|.||.|:||||||...:|:.|.||||:|:||:.|:::|.||.
Human    86 GALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150

  Fly   163 CTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYF- 226
            |..|..::||||..||.:||.|||..|||.|.|||||||||:|||..:|..|:.:|..|.:.:|
Human   151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFE 215

  Fly   227 -TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVS 290
             :||.:...|..|||:.||.||:|:||:.||::.||:|:|.:|||.:|.||..:|||:|::.||:
Human   216 NSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVA 280

  Fly   291 FYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMP 355
            :||:|...:::.|.|||||:|::.||:..|.||:.||||.||.:|..::.:||||:.|:..|.:|
Human   281 YYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLP 345

  Fly   356 EILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNL 420
            :.:.||.::||||.|::|...:::::||.|.|||.||||..|:.|..:|::::...:|||.:|:.
Human   346 DAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDR 410

  Fly   421 PRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVY--LVFIAWKNKPIWFQKT 483
            |||:::.:.||||:.:.|||:..||:|:..:.:..||.:.||.:|.|  ::.:....:|::.::.
Human   411 PRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRI 475

  Fly   484 MVSLTRFLQKMLM 496
            :.|.||:||.:.|
Human   476 VGSATRYLQVLCM 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	218/459 (47%)
SLC7A7	NP_001119577.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		3/6 (50%)
SLC7A7	NP_001119577.1	2A0308	20..493	CDD:273332	222/468 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157242
Domainoid	1	1.000	455	1.000	Domainoid score	I503
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		otm41131
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.790