DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1607 and AGP1

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_009905.3	Gene:	AGP1 / 850333	SGDID:	S000000530	Length:	633	Species:	Saccharomyces cerevisiae

Alignment Length:	553	Identity:	110/553 - (19%)
Similarity:	203/553 - (36%)	Gaps:	150/553 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SSRKSSIVNGNGDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVL 75
            |||::..:..|       .:.|..|...|....:||..:...:...:.:|:.||:|:.|.....|
Yeast    89 SSRQAQELEKN-------ESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTAL 146

  Fly    76 MYTGSVNLALIVWVISG--LFSMVGAYC------YAELGTMITKSGADYAY----IMETFGPFMA 128
            ::.|...| ||.:.|.|  |:.::.| |      |:.|      :|...||    :.:.||
Yeast   147 VHAGPAGL-LIGYAIMGSILYCIIQA-CGEMALVYSNL------TGGYNAYPSFLVDDGFG---- 199

  Fly   129 FIRLWIEC---MIVRPCSQAIVALT---FSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCW 187
            |...|:.|   :.|.|......::|   ::|.|....|            :.:..:||:| ||.:
Yeast   200 FAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVF------------VIIFYVLVIT-INIF 251

  Fly   188 DVKWATAVQDIFTYAKLLALFIIIATGVYQL-------------YLGNTQY-----FTFENTDTK 234
            ..:.....:..|...|:|.:     ||.:.|             ::|...:     |..::...:
Yeast   252 GARGYAEAEFFFNCCKILMM-----TGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDR 311

  Fly   235 VTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAI------AISCTLVTIVYVMANVSFYT 293
            ...:|.:..:..||:.|..::.....|..:|.|.:|.|.      .:...|.||:.    :.|..
Yeast   312 FKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIIL----LGFLV 372

  Fly   294 ILSPDEVMGS-------SAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANN 351
            ..:.|:::||       |...:..|.....::...|...:.||.....|....:|:|||...:..
Yeast   373 PYNSDQLLGSTGGGTKASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQ 437

  Fly   352 GQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFA-------TWLSI--GVA- 406
            |..|::.:.|.            .|...::.:.||.:||:|.:...:       |||..  |::
Yeast   438 GYAPKVFSYID------------RAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQ 490

  Fly   407 -----VLCLPWLRWAQPNLPRPIRV---------------------PMVFPIVYLIATIFVTVVP 445
                 .:||..||:.     |.::|                     ..:..|:.|||..:|.:.|
Yeast   491 LFTWTAICLSHLRFR-----RAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWVAIAP 550

  Fly   446 MYASPVET-----GYGILMILSSIPVYLVFIAW 473
            :....::.     .|..:.||  |.:|:.:..|
Yeast   551 IGEGKLDAQAFFENYLAMPIL--IALYVGYKVW 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	103/522 (20%)
AGP1	NP_009905.3	2A0310	117..597	CDD:273334	102/518 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345699
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850