DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1607 and slc7a10a

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001373301.1	Gene:	slc7a10a / 567420	ZFINID:	ZDB-GENE-080116-1	Length:	511	Species:	Danio rerio

Alignment Length:	516	Identity:	221/516 - (42%)
Similarity:	324/516 - (62%)	Gaps:	23/516 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 METESLNRKN--SSRKSSIVNGNGDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVGSII 63
            |:....||:|  .|.:..:::..|:.|         |..|   .||||.::.||:.|.:|:|:||
Zfish     1 MDGTETNRRNCAKSEQQKMLDSRGNQS---------GSKD---RVTLKKEIGLLSACAIIIGNII 53

  Fly    64 GSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMA 128
            |||||:||.|||.:.|||..:|||||:.|....:|:.||||||..|.|||.||:|:.|.||..:.
Zfish    54 GSGIFISPKGVLDHAGSVGFSLIVWVLGGGICALGSLCYAELGVTIPKSGGDYSYVTEIFGGLVG 118

  Fly   129 FIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWAT 193
            |:.||...:|:.|.:.|::|||||.|||:|.||.|.||..:.|||:..|:|.||.:||..|:|.|
Zfish   119 FLLLWSAVLIMYPTTLAVIALTFSNYVLQPAFPNCLPPYIATRLLSTTCVLFLTWVNCSSVRWGT 183

  Fly   194 AVQDIFTYAKLLALFIIIATGVYQLYLGNTQYFTFEN-------TDTKVTSIALSFYSGLFAYNG 251
            .:||:||..|||||.:||..|:.|:..|:  |...|.       .|..|..|||:|....|||:|
Zfish   184 RIQDVFTVGKLLALVLIIVVGMVQIAKGH--YDALEPQAAFEFIKDPSVGQIALAFLQASFAYSG 246

  Fly   252 WNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFG 316
            ||:||::.||:.:|.|||||||.||..|||:||.:.|:::::.:||.|::.|:|||||:.|:..|
Zfish   247 WNFLNYVTEEVVEPRKNLPRAIYISIPLVTLVYTLTNIAYFSSMSPQELLESNAVAVTFGEKLLG 311

  Fly   317 MLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSML 381
            |.:|.:|:.|||||||.:||.|.|||||.::||..|.:|.:|.||.::..||.||::.....:::
Zfish   312 MFSWVMPISVALSTFGGINGYLFTSSRLCFSGAREGHLPYLLAMIHLKSCTPIPALIVCCTATIV 376

  Fly   382 YLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPM 446
            .|.:.|...|||||.|..:||.||.:..|.:.||.:||:.|||:|.::.|..||:....:....:
Zfish   377 ILCIGDTHNLINYVSFINYLSYGVTIAGLLYYRWKKPNMFRPIKVNLLVPCSYLVFWAVLLGFSL 441

  Fly   447 YASPVETGYGILMILSSIPVYLVFIAWKNKPIWFQKTMVSLTRFLQKMLMVLGKQTKPAQV 507
            |:.||..|.|::::|:.:|:|.:.:.|||||.|....:..:|...|||..|:..|..|:::
Zfish   442 YSEPVVCGMGLVIMLTGVPIYFIGVQWKNKPQWIYSAIERVTYLGQKMCYVVFPQDDPSEI 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	210/465 (45%)
slc7a10a	NP_001373301.1	2A0308	1..497	CDD:273332	219/509 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592989
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D867824at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.760