Protein Alignment CG1607 and SLC7A10

DIOPT Version :9

• Sequence 1: NP_001263139.1
• Gene: CG1607 / 43707
• FlyBaseID: FBgn0039844
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 206/633 - (32%)
• Similarity: 312/633 - (49%)
• Gaps: 147/633 - (23%)

  Fly    19 NGNGDASAKLTNGDGDGGGDGGGE-VTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVN 82
            :|.|:.....:.....|...|..| |.||.::.||:.||:|:|:|||||||:||.|||.::|||.
Human     9 SGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVG 73

  Fly    83 LALIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIV 147
            |||.|||:.|..:.:|:.||||||..|.|||.||||:.|.||....|:.||...:|:.|.|.|::
Human    74 LALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVI 138

  Fly   148 ALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIA 212
            ::|||.|||:|.||.|.||..::|:|::.|:::||.:|...|:|||.:||:||..|||||.:||.
Human   139 SMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203

  Fly   213 TGVYQLYLGN------TQYFTFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPR 271
            .|:.|::.|:      :..|.|..|.: |..:||:|..|.||::|||:||::.||:.|..|||||
Human   204 VGLLQIFQGHFEELRPSNAFAFWMTPS-VGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPR 267

  Fly   272 AIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAE------------------------ 312
            ||.||..|||.||...|::::|.:||.|::.|:||||....
Human   268 AIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSGPLLGPWLLPRPLPRPYTWPLYCAHP 332

  Fly   313 ----RAFGML----------------AWTIPVFV----ALSTFGAVNG----------------- 336
                .|.|:|                .| :||.:    ||...|...|
Human   333 DLRGEAAGLLFLGHACLRGSVNLRRDQW-LPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGRD 396

  Fly   337 ----------------------------------------------------------------- 336
                                                                             
Human   397 TCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPKL 461

  Fly   337 --------ILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALIN 393
                    |.:.::||.::||..|.:|.:|.||.::..||.||:|.....:.:.:.|.|.:.|||
Human   462 RPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLIN 526

  Fly   394 YVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGIL 458
            ||.|..:|..||.:|.|..|||.:|.|.|||:|.::.|:.||:...|:.|....:.|:..|.|::
Human   527 YVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVI 591

  Fly   459 MILSSIPVYLVFIAWKNKPIWFQKTMVSLTRFLQKMLMVLGKQTKPAQ 506
            :||:.:|::.:.:.|::||....:...|:|.:.|::..|:..|..|.:
Human   592 IILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPEE 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	200/603 (33%)
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	202/621 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157254
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	493	1.000	Inparanoid score	I1417
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D867824at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.810