DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and slc7a1a

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_021327949.1	Gene:	slc7a1a / 559627	ZFINID:	ZDB-GENE-091116-69	Length:	651	Species:	Danio rerio

Alignment Length:	549	Identity:	114/549 - (20%)
Similarity:	209/549 - (38%)	Gaps:	122/549 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 VTLKAKMSLLNGC-------TVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMVGAY 100
            |...::.|.|:.|       .:.|||.:|:|::|. .|.:....:....::.::|:.|.|::...
Zfish    19 VNCNSEESRLSRCLNTFDLVALGVGSTLGAGVYVL-AGAVARENAGPAIVLSFLIAALASVLAGL 82

  Fly   101 CYAELGTMITKSGADYAYIMETFGPFMAFIRLW--IECMIVRPCSQAIV-ALTFSTYVLKPFFPE 162
            ||||.|..:.|:|:.|.|...|.|...|||..|  |...::...|.|.. :.||...:.|.....
Zfish    83 CYAEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSATFDELIGKHIEHF 147

  Fly   163 CTP-------------PEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATG 214
            |..             |:    :.:|..||.||.:..:.||.:..|..:||...:|.|..::.:|
Zfish   148 CRQYMSMNAPGVLAEYPD----MFSVFIILTLTGLLAFGVKESAMVNKVFTCINILVLLFMVVSG 208

  Fly   215 VY------------------------------QLYLGNTQYFTFENTDTKVTSIALSFYSGLFAY 249
            :.                              :..||...:..|..|.. ::..|..||    |:
Zfish   209 LVKGTLKNWHLDPDEILNATNSTLNATQPLPSEEMLGQGGFMPFGFTGV-LSGAATCFY----AF 268

  Fly   250 NGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSA---VAVTYA 311
            .|::.:....||:|:|.:.:|..|..|..:..:.|...:.:. |::.|..::..::   ||..|.
Zfish   269 VGFDCIATTGEEVKNPQRAIPIGIVSSLLICFVAYFGVSAAL-TMMMPYYMLDKNSPLPVAFKYV 332

  Fly   312 ERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMA 376
            .......|..:....||||  ::.|.:....|:.:|.|::|.:.:.:..|..:..||..|.:...
Zfish   333 GWEGATYAVAVGSLCALST--SLLGAMFPMPRVLWAMADDGLLFKFMAGISERTKTPIKATIMSG 395

  Fly   377 LLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQP----------------NLPRPIR 425
            .|:.:...:.|:..|::.:...|.|:..:...|:..||: ||                .:...|.
Zfish   396 FLAAIMAFLFDLKDLVDLMSIGTLLAYTLVAACVLVLRY-QPEQFSQTYHIANTHEDMEMSETIS 459

  Fly   426 VP----------------MVFP----------IVYLIATIFVTVVPMYASPVETGYGI------- 457
            .|                ::||          ....|.|..:.::.:..|.:....||
Zfish   460 TPSMGILPGVEERFSFKNLLFPDIIEPSNLSGFTVNICTSLLGLLILSFSLLAVRGGIASWNIIT 524

  Fly   458 LMILSSIPVYLVFIAWKNKPIWFQKTMVS 486
            |.:|..:.|.:.||.|:...   .||.:|
Zfish   525 LAVLFGLCVIVTFIIWRQPE---SKTKLS 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	114/549 (21%)
slc7a1a	XP_021327949.1	2A0303	4..603	CDD:273330	114/549 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593040
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850