DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and slc7a6

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001017197.1	Gene:	slc7a6 / 549951	XenbaseID:	XB-GENE-963214	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	475	Identity:	222/475 - (46%)
Similarity:	328/475 - (69%)	Gaps:	8/475 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALI 86
            ||.|...|:    ...|....:.||.::|||||.::|||::|||||||||.|||:|:.|..|:||
Frog    17 GDTSHTSTS----DSKDPQDTMQLKKEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASYGLSLI 77

  Fly    87 VWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTF 151
            :|.:.|:||::||.|||||||.|.||||.||||:|.||.|:||||||...:|:.|.|||::|:||
Frog    78 LWSLGGIFSVIGALCYAELGTTIKKSGASYAYILEAFGDFVAFIRLWTSLLIIEPTSQAVIAITF 142

  Fly   152 STYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVY 216
            :.|:::|.||.|.||..::||:|..|:.::|.|||..|||.|.|||:|||||::||..||.||:.
Frog   143 ANYLVQPVFPSCYPPYMASRLIAAACVCLITFINCAYVKWGTRVQDLFTYAKVIALIAIIITGIV 207

  Fly   217 QLYLGNTQYF--TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTL 279
            :|..|.|:.|  :|..:......|:|..||.||:|:||:.|||:.||:|:|.:|||.:|.||..|
Frog   208 KLSQGQTENFEDSFAGSSWDAGEISLGLYSALFSYSGWDTLNFVTEEIKNPERNLPLSIGISMPL 272

  Fly   280 VTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRL 344
            |||:|::.||::||:|..:.|:.|.|||||:|:..:|:.:|||||.||||.||.:|..:|.:|||
Frog   273 VTIIYILTNVAYYTVLDFNAVVASEAVAVTFADMVYGVFSWTIPVAVALSCFGGLNSSILAASRL 337

  Fly   345 FYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLC 409
            |:.||..|.:|::|.:|..:||||.||:|...:.:::||.|.|:|.||||..|:.|..:|:::..
Frog   338 FFVGAREGHLPDMLCLIHQERFTPVPALLFNCVATLIYLAVKDVFQLINYYSFSYWFFVGLSIAG 402

  Fly   410 LPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYL--VFIA 472
            ..:||..:|.||||:::.:.:|||:.:.|:|:.:||:|:..|.:..||.:.||.||||.  :::.
Frog   403 QIYLRIKKPELPRPVKLSLFYPIVFCLCTVFLVIVPLYSDTVNSLIGIGIALSGIPVYFMGIYLP 467

  Fly   473 WKNKPIWFQKTMVSLTRFLQ 492
            ...:|.:..:.:..|||..|
Frog   468 ESKRPPFISRVLAFLTRRTQ 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	217/455 (48%)
slc7a6	NP_001017197.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31		5/17 (29%)
slc7a6	NP_001017197.1	2A0308	29..496	CDD:273332	218/459 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	449	1.000	Domainoid score	I513
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62496
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		otm48337
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.960