DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a8

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_058668.1	Gene:	Slc7a8 / 50934	MGIID:	1355323	Length:	531	Species:	Mus musculus

Alignment Length:	508	Identity:	246/508 - (48%)
Similarity:	340/508 - (66%)	Gaps:	19/508 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 METESLNRKNSSRKSSIVNGNGDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGS 65
            ||..:..|.|:::.....:.:.:|.|          ..|||.|.||.::.|::.|.:|||:||||
Mouse     1 MEKGARQRNNTAKNHPGSDTSPEAEA----------SSGGGGVALKKEIGLVSACGIIVGNIIGS 55

  Fly    66 GIFVSPTGVLMYTGSVNLALIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFI 130
            ||||||.|||...|||.||||||:::|:.:.|||.||||||..|.|||.||:|:.:.||....|:
Mouse    56 GIFVSPKGVLENAGSVGLALIVWIVTGIITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFL 120

  Fly   131 RLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAV 195
            ||||..:::.|.:||::|||||.|||:|.||.|.|||...||||..|:|:||.:||..|:|||.|
Mouse   121 RLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRV 185

  Fly   196 QDIFTYAKLLALFIIIATGVYQLYLGNTQYF------TFEN-TDTKVTSIALSFYSGLFAYNGWN 253
            |||||..|||||.:||..|:.|:..|  ::|      .||| .:..:..:||:|..|.|||.|||
Mouse   186 QDIFTAGKLLALALIIIMGIVQICKG--EFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWN 248

  Fly   254 YLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFGML 318
            :||::.|||.||.|||||||.||..|||.|||.||:::.|.:||.|::.|:|||||:.|:..|::
Mouse   249 FLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLASNAVAVTFGEKLLGVM 313

  Fly   319 AWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYL 383
            ||.:|:.|||||||.|||.|.||||||:|||..|.:|.:|.||.::|.||.||:|...|.::|.|
Mouse   314 AWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCLSTLLML 378

  Fly   384 TVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYA 448
            ..||::.|||||||..:|..||.|.....|||.:|::||||:|.::|||:||:...|:.:..:::
Mouse   379 VTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKVSLLFPIIYLLFWAFLLIFSLWS 443

  Fly   449 SPVETGYGILMILSSIPVYLVFIAWKNKPIWFQKTMVSLTRFLQKMLMVLGKQ 501
            .||..|.|:.::|:.:|||.:.:.|::||..|...:.|||...|||.:|:..|
Mouse   444 EPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFNDFIKSLTLVSQKMCVVVYPQ 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	236/465 (51%)
Slc7a8	NP_058668.1	2A0308	1..497	CDD:273332	246/508 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		6/37 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	499..531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847653
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	LDO	PTHR11785
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.790