DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a6

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_006531198.1	Gene:	Slc7a6 / 330836	MGIID:	2142598	Length:	532	Species:	Mus musculus

Alignment Length:	468	Identity:	229/468 - (48%)
Similarity:	333/468 - (71%)	Gaps:	7/468 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DGGGDGGGE---VTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFS 95
            |.|....|.   :.||.::|||||.:::||::|||||||||.|||.||.|..|:||||.|.||||
Mouse    44 DAGSPSQGSPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLSLIVWAIGGLFS 108

  Fly    96 MVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFF 160
            :|||.|||||||.||||||.||||:|.||.|:||||||:..:||.|.||||:|:||:.|::||.|
Mouse   109 VVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSF 173

  Fly   161 PECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQY 225
            |.|.||..:.||||..|:.:||.:||..|||.|.|||.|||||:|||..||..|:.:|..|:|::
Mouse   174 PTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQGHTEH 238

  Fly   226 F--TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMAN 288
            |  .|:.:...|..::|:.||.||:|:||:.|||:.||:|:|.:|||.||.||..:||::|::.|
Mouse   239 FQDAFKGSSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTN 303

  Fly   289 VSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQ 353
            |::||:|:..:|..|.|||||:|::.|||.:||||:.||||.||.:|..:..|||||:.|:..|.
Mouse   304 VAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGH 368

  Fly   354 MPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQP 418
            :|.:|:||.|:||||.||:|....::::||.|.|:|.||||..|:.|..:|::|:...:|||.:|
Mouse   369 LPNLLSMIHIERFTPVPALLFNCTMTLIYLVVKDVFLLINYFSFSYWFFVGLSVVGQLYLRWKEP 433

  Fly   419 NLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYL--VFIAWKNKPIWFQ 481
            :.|||:::.:.||||:.:.::|:..||:::..:.:..||.:.||.:|||.  |::....:|::.:
Mouse   434 DWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDTINSLIGIGIALSGVPVYFLGVYLPESRRPLFIR 498

  Fly   482 KTMVSLTRFLQKM 494
            ..:.::||..||:
Mouse   499 NVLATVTRVTQKL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	226/460 (49%)
Slc7a6	XP_006531198.1	2A0308	34..518	CDD:273332	229/468 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847669
Domainoid	1	1.000	459	1.000	Domainoid score	I488
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62496
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2022
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		otm43198
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.640