DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and CG12531

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_608350.2	Gene:	CG12531 / 32986	FlyBaseID:	FBgn0031064	Length:	812	Species:	Drosophila melanogaster

Alignment Length:	421	Identity:	99/421 - (23%)
Similarity:	173/421 - (41%)	Gaps:	89/421 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VGSIIGSGIF---------VSPTGVLMYTGSVNLALIVWVISGLFSMVGAYCYAELGTMIT-KSG 113
            :||..|:|::         ::..||:       ::.|:..|:.:||  || ||||.|..:. .||
  Fly    67 IGSCCGTGMYLVAGMVAQKIAGPGVI-------ISFIIAAIASIFS--GA-CYAEFGVRVPHTSG 121

  Fly   114 ADYAYIMETFGPFMAFIRLW---IECMI-VRPCSQAI-----------VALTFSTYVLKPFFPEC 163
            :.|.|.....|.|:|||..|   :|.:| ...|:.|:           :|.|.|..:...|   .
  Fly   122 SAYMYSYVAVGEFVAFIIGWNMILEYLIGTSACACALSSSFDSLTGNAIARTISESIGTIF---G 183

  Fly   164 TPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYFTF 228
            .||:    .:|....|::|.:.......:...........|.....::|.|::.:
  Fly   184 KPPD----FIAFGITLLMTCVLAMGASKSVIFNHSLNAVNLATWVFVMAAGLFYV---------- 234

  Fly   229 ENTDTKVTSIALSF----YSGLF--------AYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVT 281
               |||..|....|    :||:|        |:.|::.:....||..:|.|::|:||..|..:|.
  Fly   235 ---DTKTWSEHQGFLPYGWSGVFSGAATCFYAFIGFDIIATTGEEAHNPQKSIPKAIVGSLVVVL 296

  Fly   282 IVYVMANVSFYTILSPDEVMGSSAVAV---TYAE----RAFGMLAWTIPVFVALSTFGAVNGILL 339
            |.||..:: ..|::.|.:.:.:.|..|   :|..    ||...:..|..:.||:  ||:    :.
  Fly   297 IAYVSVSL-VLTLVVPYDHINTGAALVQMWSYVNAPKCRAVVAIGATAGLSVAM--FGS----MF 354

  Fly   340 TSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIG 404
            ...|:.||.|.:|.:...|:.:..:...|..|.:...|.:.|......:..|:..:...|.|:..
  Fly   355 PMPRVIYAMAQDGLIFRQLSQLWHRTNVPGLATIGSGLAAALVALTVRLEILVEMMSIGTLLAYT 419

  Fly   405 VAVLCLPWLRWAQPN-------LPRPIRVPM 428
            :...|:..||: ||:       ||..:|.|:
  Fly   420 LVSTCVLVLRY-QPHSTSLVELLPAQLRTPV 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	99/421 (24%)
CG12531	NP_608350.2	2A0303	52..679	CDD:273330	99/421 (24%)
CG12531	NP_608350.2	AA_permease_C	629..679	CDD:290617
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466561
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.870