DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a13

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001012100.1	Gene:	Slc7a13 / 313089	RGDID:	1311633	Length:	479	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	146/465 - (31%)
Similarity:	255/465 - (54%)	Gaps:	17/465 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 EVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTG-SVNLALIVWVISGLFSMVGAYCYAEL 105
            ::.||.::....|...::.:|||:||||||.|||.|:. :|.::|.|||...:.||....|.||:
  Rat     8 KIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEI 72

  Fly   106 GTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSA 170
            |.....:.|.|.::...||||:||:|||.. :...|...|..||..:.|.::||:|.|:.|....
  Rat    73 GITFPYTVAHYYFLKRCFGPFVAFLRLWTS-LFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPK 136

  Fly   171 RLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYF-----TFEN 230
            :.||:..:.::.::|...||..:.:|.:....|:..|..|..:|::.|..|..:..     .|:.
  Rat   137 KCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDA 201

  Fly   231 TDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTIL 295
            ...:|:.:..:.:.|.||::|.....::..|||:|.|.:||.|..:..|||:||::||:|:.|:|
  Rat   202 EFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVL 266

  Fly   296 SPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTM 360
            ||.|::.|.|||:|:.:|....|.|::|..::.|.|..:...:..:||..|..:.|||:|.:.:.
  Rat   267 SPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCST 331

  Fly   361 IQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIR 425
            :.:.. :|..|||....:..:.:.::::..||||:.|...:...::|:.:..||:.:|||.||.:
  Rat   332 LNVHS-SPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYK 395

  Fly   426 VPMVFPIVYLIATIFVTVV--PMYASP-VETGYGILMILSSIPVYLVFIAWKNKPIWFQKTMVSL 487
            |  ..|.:::.|.|.:::|  |:..|| ::..|..|..|..:..|:..|.:|.|.|||||    |
  Rat   396 V--FSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQK----L 454

  Fly   488 TRFLQKMLMV 497
            |.:||.:..:
  Rat   455 TCYLQLLFNI 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	146/465 (31%)
Slc7a13	NP_001012100.1	PotE	11..454	CDD:223605	142/450 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740