DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a11

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_038958186.1	Gene:	Slc7a11 / 310392	RGDID:	1309275	Length:	505	Species:	Rattus norvegicus

Alignment Length:	480	Identity:	205/480 - (42%)
Similarity:	315/480 - (65%)	Gaps:	3/480 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALI 86
            |:.|.:|.: .||....|..:|.||.|::||.|.::|:|::||||||:||.|:|..||||.::|:
  Rat    18 GNVSGRLPS-VGDQEPPGHEKVVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGSVGMSLV 81

  Fly    87 VWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTF 151
            .|...|:.|:.||..||||||.|.|||..|.||:|.|||.:||:|:|:|.:::||.:.|:::|.|
  Rat    82 FWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAF 146

  Fly   152 STYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVY 216
            ..|:|:|||.:|..||.:.:|:....|.|:.::|...|.|:..:|...|:.||.|:.|||..||.
  Rat   147 GRYILEPFFIQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVI 211

  Fly   217 QLYLGNTQYF--TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTL 279
            ||..|.|.:|  .|...||.:..:.|:||.|::||.||.|||||.||:.:|.|.:|.||.||..:
  Rat   212 QLIKGQTHHFKDAFSGRDTNLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAI 276

  Fly   280 VTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRL 344
            :|:.||:.||:::|.:|.:|::.|||||||::||..|..:..:|:|||||.||::||.:...|||
  Rat   277 ITVGYVLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVALSCFGSMNGGVFAVSRL 341

  Fly   345 FYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLC 409
            ||..:..|.:||||:||.:.:.||.|||:.:..|:|:.|...|:::|:|::.||.||.:|:||..
  Rat   342 FYVASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMIMLFSGDLYSLLNFLSFARWLFMGLAVAG 406

  Fly   410 LPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYLVFIAWK 474
            |.:||:.:|::.||.:||:..|.::....:|:.|:.:|:.|..||.|.|:.|:.:|.|.:||.|.
  Rat   407 LIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDPFSTGVGFLITLTGVPAYYLFIVWD 471

  Fly   475 NKPIWFQKTMVSLTRFLQKMLMVLG 499
            .||.||::..|:...|..|...:.|
  Rat   472 KKPKWFRRLSVNNLHFSLKSTFLCG 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	199/460 (43%)
Slc7a11	XP_038958186.1	2A0308	1..482	CDD:273332	201/464 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860