DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a6

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_006255560.1	Gene:	Slc7a6 / 307811	RGDID:	1309193	Length:	528	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	230/468 - (49%)
Similarity:	334/468 - (71%)	Gaps:	5/468 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 DGDGGGDGGGE-VTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFS 95
            |......|..| :.||.::|||||.:::||::|||||||||.|||.||.|..|:|:||.|.||||
  Rat    40 DASSPSQGSPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLSLVVWAIGGLFS 104

  Fly    96 MVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFF 160
            :|||.|||||||.||||||.||||:|.||.|:||||||:..:||.|.||||:|:||:.|::||.|
  Rat   105 VVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSF 169

  Fly   161 PECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQY 225
            |.|.||..:.||||..|:.:||.:||..|||.|.|||.|||||:|||..||..|:.:|..|:|::
  Rat   170 PTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQGHTEH 234

  Fly   226 F--TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMAN 288
            |  .|:.:...|..::|:.||.||:|:||:.|||:.||:|:|.:|||.||.||..:||::|::.|
  Rat   235 FQDAFKGSSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTN 299

  Fly   289 VSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQ 353
            |::||:|:..:|..|.|||||:|::.|||.:||||:.||||.||.:|..:..|||||:.|:..|.
  Rat   300 VAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGH 364

  Fly   354 MPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQP 418
            :|.:|:||.|:||||.||:|....::::||.|.|:|.||||..|:.|..:|::|:...:|||.:|
  Rat   365 LPNLLSMIHIERFTPVPALLFNCTMTLIYLVVKDVFLLINYFSFSYWFFVGLSVVGQLYLRWKEP 429

  Fly   419 NLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYL--VFIAWKNKPIWFQ 481
            :.|||:::.:.||||:.|.::|:..||:::..:.:..||.:.||.:|||.  |::....:|::.:
  Rat   430 DWPRPLKLSLFFPIVFCICSLFLVAVPLFSDTINSLIGIGIALSGVPVYFMGVYLPEARRPLFIR 494

  Fly   482 KTMVSLTRFLQKM 494
            |.:.::||..||:
  Rat   495 KVLATVTRVTQKL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	228/458 (50%)
Slc7a6	XP_006255560.1	2A0308	30..514	CDD:273332	230/468 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351231
Domainoid	1	1.000	459	1.000	Domainoid score	I462
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62496
Inparanoid	1	1.050	489	1.000	Inparanoid score	I1363
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		otm45273
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.710