DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a12

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001011948.1	Gene:	Slc7a12 / 294881	RGDID:	1309208	Length:	472	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	135/448 - (30%)
Similarity:	230/448 - (51%)	Gaps:	30/448 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 MSLLNGC------TVIVGSIIGSGIFVSPTGVLMYTG-SVNLALIVWVISGLFSMVGAYCYAELG 106
            |.||.|.      ..:..:.||:||||||.|||.|.. ::.:.|.:|...||.||:.|.|.||:.
  Rat     1 MQLLRGLGFFHVNMFLFSATIGTGIFVSPKGVLKYCSLNIPIFLSIWAGCGLLSMMNAVCLAEIA 65

  Fly   107 TMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVA--LTFSTYVLKPFFPECTPPEDS 169
            .....|||.|.::....|..:||:.:||:   :..|:..|.|  |..::.:::.|:.||..||..
  Rat    66 ATYPVSGASYYFLKRALGSSVAFLSIWIK---IFACTLGISAQCLLIASSLIQCFYSECQAPELP 127

  Fly   170 ARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLG---NTQYF--TFE 229
            .:.||:..:....:::...:|.......|.:..||..|.:|..||:..|.:|   |...|  ..|
  Rat   128 KKCLALAILWSFGILSARGIKPVAWFNTISSLMKLSVLCLISLTGIVLLVIGKKENVSRFEKALE 192

  Fly   230 NTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTI 294
            .....|:.||.:.....:||.|.::|..|..|:|.|.:.:|::|....::||::|::.||||..:
  Rat   193 AELPNVSQIAEAILQVYYAYLGSSFLIVIAGEIKRPAETIPKSIIYGLSVVTVLYLLTNVSFLAV 257

  Fly   295 LSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILT 359
            |:.:|::.|.:||||:..|.|..:.|.|.:.::...||:|:..::::||:|||.:..||.|.|.:
  Rat   258 LTSEEIISSDSVAVTWMNRVFPSMQWIISLLISAFLFGSVSCGIVSASRIFYATSQEGQFPFIYS 322

  Fly   360 MIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPI 424
            |:. ...:|..|.|...:||.:.:..|::..||.|||..||....:.::.|..||:..|:||||.
  Rat   323 MLN-DLHSPVVADLQAVILSSVGIISSNMIYLIKYVGLGTWCLNLLNMIGLLKLRYQNPDLPRPY 386

  Fly   425 RVPMVFPIVYLIATIFVTVVPMYASP-VETGYGILMILSSIPVYLVFIAWKNKPIWFQ 481
            :|.:.|....:.:::|:.:.|:..|| .|..|.::.:...:..|           |.|
  Rat   387 KVRLPFVFGSIASSLFLILTPVIQSPSTEHVYQVVFLFCGLLCY-----------WLQ 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	135/448 (30%)
Slc7a12	NP_001011948.1	2A0308	21..423	CDD:273332	128/405 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740