DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and Slc7a1

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_037243.2	Gene:	Slc7a1 / 25648	RGDID:	3716	Length:	624	Species:	Rattus norvegicus

Alignment Length:	529	Identity:	129/529 - (24%)
Similarity:	224/529 - (42%)	Gaps:	92/529 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 GEVTLKAKM-------SLLNGC-------TVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVIS 91
            |:.||:.|:       |.|:.|       .:.|||.:|:|::|. .|.:....:....:|.::|:
  Rat    10 GQQTLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVL-AGAVARENAGPAIVISFLIA 73

  Fly    92 GLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLW--IECMIVRPCSQAIV-ALTFST 153
            .|.|::...||.|.|..:.|:|:.|.|...|.|...|||..|  |...|:...|.|.. :.||..
  Rat    74 ALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDE 138

  Fly   154 YVLKPF------FPECTPPEDSAR---LLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFI 209
            .:.||.      ......|...|:   :.||..|::||.:....||.:..|..|||...:|.|..
  Rat   139 LIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCF 203

  Fly   210 IIATGVYQLYLGNTQYFTFE------NTDTKVTSIALSF----YSGL--------FAYNGWNYLN 256
            |:.:|..:..:.|.|....:      |.||.|......|    :||:        :|:.|::.:.
  Rat   204 IMVSGFVKGSIENWQLTENKSSPLCGNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIA 268

  Fly   257 FIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGS-SAVAVTYAERAFGMLAW 320
            ...||:|:|.|.:|..|..|..:..|.|...:.:. |::.|...:.: |.:...:..|.:....:
  Rat   269 TTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAAL-TLMMPYFCLDTDSPLPGAFKYRGWEEAKY 332

  Fly   321 TIPV--FVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYL 383
            .:.|  ..||||  ::.|.:....|:.||.|.:|.:.:.|..|..:..||..|.:....::.:..
  Rat   333 AVAVGSLCALST--SLLGSMFPMPRVIYAMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMA 395

  Fly   384 TVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIA--TIFVTVVP- 445
            .:.::..|::.:...|.|:..:...|:..||: ||..|.         :||.:|  |..:..|.
  Rat   396 FLFELKDLVDLMSIGTLLAYSLVAACVLVLRY-QPEQPN---------LVYQMARTTDELDQVDQ 450

  Fly   446 ---MYASPVETG-------YGILMILSSIPVYLVFIAWKN-KPIWFQKTMVSLTRFLQKMLM--- 496
               :.||..:||       :.:..|||.          || :|..|...:|:::..|..:|:
  Rat   451 NEMVSASESQTGFLPAAEKFSLKTILSP----------KNMEPSKFSGLIVNISAGLLAVLIITV 505

  Fly   497 ----VLGKQ 501
                |||::
  Rat   506 CIVAVLGRE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	128/526 (24%)
Slc7a1	NP_037243.2	2A0303	4..605	CDD:273330	129/529 (24%)
Slc7a1	NP_037243.2	AA_permease_C	553..603	CDD:290617
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351230
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940