DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1607 and put4

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_595009.1	Gene:	put4 / 2543679	PomBaseID:	SPAC869.10c	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	548	Identity:	117/548 - (21%)
Similarity:	210/548 - (38%)	Gaps:	114/548 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ETESLNRKNSSRKSSIVN------GNGDASAKLTNGDGDGGGDGGGEVTLKAKMSLLNGCTVIVG 60
            |.::|..:.|.|...|.:      |..|...|.          |..:..||::...|    :.:|
pombe     3 EKKALQYEESKRAEEITDIELVSVGGIDVEKKY----------GETKRALKSRHVQL----IAIG 53

  Fly    61 SIIGSGIFVSPTGVLMYTGSVNLAL-------IVWVISGLFSMVGAYCYAELGTMITKSGAD-YA 117
            ..||:|:||.....|..:|..:|.|       ::|.:   .:.:|..|     |.:..|||. ..
pombe    54 GCIGTGLFVGSGSALSESGPASLFLSYVIMSFVIWTV---MNALGEMC-----TYLPLSGASPIT 110

  Fly   118 YIMETFGPFMAFIRLW-----IECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCC 177
            ||.......:||...|     ...::....:.|.:.:.:.||.:           .:|..:|:..
pombe   111 YIERYVDASLAFAAGWNYWYAYVFLVASEVTAASIVIEYWTYAV-----------PTAGWIAILL 164

  Fly   178 ILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNT--------QYF----TFEN 230
            .|| .::|.:.|||....:..|...|::|:..:|..||. ::.|.|        :|:    .|..
pombe   165 FLV-AVLNSFFVKWFGETEFWFAIIKVIAIVGLIILGVV-IFFGGTPKHDRLGFRYWKHGLAFRE 227

  Fly   231 TDTK-VTSIALSFYSGLFAYNGWNYL------NFIIEELKDPVKNLPRAIAISCTLVTIVYVMAN 288
            ...| .:...:.|:|.:.. :|:.::      .|...|.:.|.:|:|:|.:.....:...|:..:
pombe   228 YIVKGASGRFVGFWSAVIK-SGFAFILAPELVIFSAGETEAPRRNIPKATSRFIYRLIFFYIFGS 291

  Fly   289 VSFYTILSPDE-----VMGSSAVAVTYAERAFGMLAWTIPVF-------VALSTFGAVNGILLTS 341
            ::...|.|..:     .:.|.|.....:....|:....|||.       :..|...:.|..|...
pombe   292 LTIGVITSSKDPRLLNAISSGASGAAASPFVIGIQNAEIPVLNHIINAVILTSACSSGNSFLFAG 356

  Fly   342 SRLFYAGANNGQMPEILTMIQIQRF-TPTPAVLAMALLSML-YLTVSDIFALI-NYV-------G 396
            ||..|:.|...|.|:|..  ...|: .|..:|....|.:.| :|..|...|:: |:.       |
pombe   357 SRSIYSLAKEHQAPKIFK--YCNRWGVPVISVAVTVLFACLAFLNASASAAVVFNWFCNLSTISG 419

  Fly   397 FATWLSIGVAVLCLPWLRWAQ--PNL--PRPIRVPM----VFPIVYLIATIFVT-VVPMYASPVE 452
            |..|:.:.||.|   ..|.|.  .||  .||.:.|.    .:..::|:|.|.:| ...::.....
pombe   420 FLAWICVLVAYL---QFRKAMILNNLWETRPYKTPFQPYATYLTLFLLALITLTNGFTVFVGHTF 481

  Fly   453 TGYGILMILSSIPVYLV-FIAWKNKPIW 479
            |....:....::|::|| ::|.|   :|
pombe   482 TAGNFIAAYITLPIFLVLYVAHK---LW 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	108/502 (22%)
put4	NP_595009.1	LysP	10..551	CDD:223903	115/541 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I2720
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I1939
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060