DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1607 and SPCC965.11c

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_588521.1	Gene:	SPCC965.11c / 2539173	PomBaseID:	SPCC965.11c	Length:	537	Species:	Schizosaccharomyces pombe

Alignment Length:	563	Identity:	114/563 - (20%)
Similarity:	205/563 - (36%)	Gaps:	120/563 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 METESLNRKNSSRKSSIVNGNGDASAKLTNGDGDGGGDG--GGEVTLKAKMSLLNGCTVIVGSII 63
            ||.....:..:.:.||..|.:...|..:|....:...:|  .|..|....|..|.|       ||
pombe     1 MEAAPSEKVPAKKLSSSENLDIGVSEVVTVDAAENNSNGIKRGLKTRHVSMMALAG-------II 58

  Fly    64 GSGIFVSPTGVLMYTGSVNL----ALIVWVISGLFSMVGAYCYAELGTMITKSGADYA--YIMET 122
            |.|:|:.....|...|.|.|    |::..|:.|:...:|     |..::...:...:|  ::...
pombe    59 GPGVFIGMGSALHIGGPVGLIVGFAIVSIVVFGVMLSIG-----EFNSLFDFNFNTHAARWVDPA 118

  Fly   123 FGPFMA--FIRLWIECMIVRPCSQAIVALTFSTYVLKP---FFPECTPPEDSARLLAVCCILVLT 182
            ||..:.  ::.:|:..:.....|...:...:..:|  |   ||                 ::...
pombe   119 FGAAIGWNYVIVWLTNIAAEYTSLTSILQYWGPHV--PSYGFF-----------------LIFWG 164

  Fly   183 LINCWDVKWATAVQD---IFTYAKLLALFIIIATGVYQLYL----GNTQYFTFENTDTKVTSIAL 240
            ...|:.:...:...:   |..:.||  |||   ||.|...:    |...:....|. .|...:|.
pombe   165 FFTCYQMLGVSVFGESEYILAFIKL--LFI---TGFYIFAIIYAAGGIPHHKPPNL-FKEMPLAH 223

  Fly   241 SF--------YSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSF-YTIL- 295
            .|        |:|:| ::|...::....|.|:|.|.:|  :|:..|...|:||...:|. |.|.
pombe   224 GFGGIVSAFVYAGVF-FSGVESVSMTAAESKNPKKAIP--LAVRQTFWRILYVYFGISISYGITV 285

  Fly   296 ---SPDEVMGS----SAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQ 353
               .|:...||    |.:.:......:......:...:.::...::|..:...||..|..|.:|.
pombe   286 AWNDPNLSSGSKTLKSPMTIAIMNAGWNHAGDFVNAVILITCLSSINSGIYIGSRSLYNLAKDGM 350

  Fly   354 MPEILTMIQIQRFTPTPAVLAMAL---LSMLYLTVSDIFA---LINYVG---FATWLSI------ 403
            .|:|...:. :|..|..||.::.|   ||::..:...:.|   :||..|   |..|.:|
pombe   351 APKIFKRVD-KRGVPWVAVHSVHLFGFLSIMNYSTGAVKAYGYIINLAGVSAFIVWTAIIFVHFR 414

  Fly   404 --------GVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMI 460
                    |.|:..||   :..|..|.|..:..|..|:..:...:....|..|......|.:|
pombe   415 FRRGWVKQGYALSDLP---FKSPLYPFPQLIGFVIGIILTLVQGWTVFKPFAAGDFVDAYILL-- 474

  Fly   461 LSSIPVYLVFIAWKNKPIWFQKTMVSLTRFL--QKMLMVLGKQ 501
                |::.|        ||.....:..|:::  :.|..:.|::
pombe   475 ----PLFFV--------IWLSYKFIKKTKWVSYEDMDFINGRR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	105/518 (20%)
SPCC965.11c	NP_588521.1	LysP	1..537	CDD:223903	114/563 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I2720
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I1939
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060