Protein Alignment CG1607 and SLC7A11

DIOPT Version :9

• Sequence 1: NP_001263139.1
• Gene: CG1607 / 43707
• FlyBaseID: FBgn0039844
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_011530104.1
• Gene: SLC7A11 / 23657
• HGNCID: 11059
• Length: 506
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 205/481 - (42%)
• Similarity: 313/481 - (65%)
• Gaps: 15/481 - (3%)

  Fly    14 KSSIVNGNGDASAKLTNGD----GDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGV 74
            |...:.||       .||.    |:....|..:|.||.|::||.|.::|:|:|||:|||:||.||
Human    12 KGGYLQGN-------VNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGV 69

  Fly    75 LMYTGSVNLALIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIV 139
            |..||||.::|.:|.:.|:.|:.||..||||||.|.|||..|.||:|.|||..||:|:|:|.:|:
Human    70 LQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLII 134

  Fly   140 RPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKL 204
            ||.:.|:::|.|..|:|:|||.:|..||.:.:|:....|.|:.::|...|.|:..:|...|:.||
Human   135 RPAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKL 199

  Fly   205 LALFIIIATGVYQLYLGNTQYF--TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVK 267
            .|:.|||..||.||..|.||.|  .|...|:.:|.:.|:||.|::||.||.||||:.||:::|.|
Human   200 TAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEK 264

  Fly   268 NLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFG 332
            .:|.||.||..:|||.||:.||:::|.::.:|::.|:|||||::||..|..:..:|:|||||.||
Human   265 TIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFG 329

  Fly   333 AVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGF 397
            ::||.:...|||||..:..|.:||||:||.:::.||.|||:.:..|:|:.|...|:.:|:|::.|
Human   330 SMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSF 394

  Fly   398 ATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILS 462
            |.||.||:||..|.:||:..|::.||.:||:..|.::....:|:..:.:|:.|..||.|.::.|:
Human   395 ARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLT 459

  Fly   463 SIPVYLVFIAWKNKPIWFQKTMVSLT 488
            .:|.|.:||.|..||.||:  ::|:|
Human   460 GVPAYYLFIIWDKKPRWFR--IMSVT 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	198/449 (44%)
SLC7A11	XP_011530104.1	2A0308	1..483	CDD:273332	204/479 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157265
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.860