DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and SLC7A13

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_620172.2	Gene:	SLC7A13 / 157724	HGNCID:	23092	Length:	470	Species:	Homo sapiens

Alignment Length:	475	Identity:	149/475 - (31%)
Similarity:	248/475 - (52%)	Gaps:	29/475 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYT-GSVNLALIVWVISGLFSMVGAYC 101
            |.|.::.||.......|.:.::.:|||:||||||.|||.|: .:|.::|.||....:.:|....|
Human     2 DRGEKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLC 66

  Fly   102 YAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIV---ALTFSTYVLKPFFPEC 163
            .||:......|||.|.::...||..:||:.||....:    ...:|   ||..:.|.::||||.|
Human    67 SAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFL----GSGVVAGQALLLAEYSIQPFFPSC 127

  Fly   164 TPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLG---NTQY 225
            :.|:...:.||:..:.::.::....||..|.:|...:..|:..|..|..|||..|..|   |.:.
Human   128 SVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKKENVER 192

  Fly   226 F--TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMAN 288
            |  .|:.....::.:..:.:.|.|||:|......|..|||.|...:|:.|..:..|||:||::.|
Human   193 FQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLVTVVYLLVN 257

  Fly   289 VSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQ 353
            :|:.|:|:|.|::.|.|||:|:|:|||..|||.:|..::.|.|..:...:..|||..|..:..||
Human   258 ISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISIFKSSRPIYLASQEGQ 322

  Fly   354 MPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGF--ATW---LSIGVAVLCLPWL 413
            :|.:...:. ...:|..|||.:..|..|.:.::.:..||||:.|  :.|   |.||:.     ..
Human   323 LPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFTGSLWSILLMIGIL-----RR 381

  Fly   414 RWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASP-VETGYGILMILSSIPVYLVFIAWKNKP 477
            |:.:|||..|.:|.:.||:..::..:.:.|:|:..|| |...|.:|::||.:..|:..|.:|.:.
Human   382 RYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHYVYVLLLVLSGLLFYIPLIHFKIRL 446

  Fly   478 IWFQKTMVSLTRFLQKMLMV 497
            .||:|    :|.:||.:..:
Human   447 AWFEK----MTCYLQLLFNI 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	147/471 (31%)
SLC7A13	NP_620172.2	AA_permease_2	16..398	CDD:290254	125/391 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157280
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740