DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and slc7a8b

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_001346314.3	Gene:	slc7a8b / 100007990	ZFINID:	ZDB-GENE-030616-586	Length:	501	Species:	Danio rerio

Alignment Length:	470	Identity:	231/470 - (49%)
Similarity:	317/470 - (67%)	Gaps:	5/470 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMVG 98
            |...||...||||.::.||:.|.::||:||||||||||.|||..:|||.||||||:::|:.:.:|
Zfish    15 DSDPDGEPAVTLKKEIGLLSACGIVVGNIIGSGIFVSPKGVLENSGSVGLALIVWILTGIITAIG 79

  Fly    99 AYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPEC 163
            |.||||||..|.|||.||:|:.:.||....|:||||..:::.|.:||::||||:.|.|:|.||.|
Zfish    80 ALCYAELGVTIPKSGGDYSYVNDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFANYALQPLFPSC 144

  Fly   164 TPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYFTF 228
            .|||.:..|||..|:|:||.|||..|:|||.|||:||..|||||.:||..|:.|:..|:..:...
Zfish   145 FPPERALGLLAAVCLLLLTWINCSSVRWATRVQDVFTTGKLLALGLIIIMGIVQICKGHFYWLEP 209

  Fly   229 ENT-----DTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMAN 288
            |:.     ...:..|||:...|.|||.|||:||::.|||.||.:||||||.||..|||.|||.||
Zfish   210 EHAFHPLQPYDMGRIALAVLQGSFAYAGWNFLNYVTEELIDPYRNLPRAIFISIPLVTFVYVSAN 274

  Fly   289 VSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQ 353
            :::.|.:||.|::.|:|||||:.|:..|:::|.:|:.|||||||.|||.|.||||||:|||..|.
Zfish   275 IAYVTAMSPQELLASNAVAVTFGEKLLGVMSWLMPISVALSTFGGVNGSLFTSSRLFFAGAREGH 339

  Fly   354 MPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQP 418
            :|.:|.||.:.|.||.||:|...:.::|.|.||||:.|||||||..:|..||.|.....||..:|
Zfish   340 LPRLLAMIHVNRCTPIPALLITCISTLLMLCVSDIYTLINYVGFINYLFYGVTVAGQIVLRIREP 404

  Fly   419 NLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYLVFIAWKNKPIWFQKT 483
            ::.|||:|.:.:|.|:||...|:.:..:|:.||....|:.::||.:||||..|.|:|||..|...
Zfish   405 DIYRPIKVSLAWPAVFLIFWAFLLIFSLYSEPVVCCIGLAIMLSGVPVYLFGIYWENKPKSFSSF 469

  Fly   484 MVSLTRFLQKMLMVL 498
            :..||...||:.:|:
Zfish   470 VARLTHLGQKLCLVV 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	228/462 (49%)
slc7a8b	XP_001346314.3	AA_permease_2	9..488	CDD:330980	231/470 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593022
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.760