DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1607 and slc7a3b

DIOPT Version :9

Sequence 1:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_001342962.3	Gene:	slc7a3b / 100003376	ZFINID:	ZDB-GENE-120813-6	Length:	698	Species:	Danio rerio

Alignment Length:	484	Identity:	111/484 - (22%)
Similarity:	199/484 - (41%)	Gaps:	118/484 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SSRKSSIVNGNGDASAKLTNGDGDGGGDGGGEVTLKAK--------------MSLLNGCTVIVGS 61
            ||..|||:..|..||.              |::.|:.:              ::.|:...:.||:
Zfish    46 SSTSSSIMTKNKLASF--------------GKMLLRRRVLDDSPVESHFARCLTTLDLIALGVGA 96

  Fly    62 IIGSGIFV----------SPTGVLMYTGSVNLALIVWVISGLFSMVGAYCYAELGTMITKSGADY 116
            .:|:|::|          .|..||.:           :|:.|.|::...||||.|..:.|:|:.|
Zfish    97 TLGAGVYVLAGEVAREKAGPAIVLSF-----------LIAALSSVLAGLCYAEFGARVPKTGSAY 150

  Fly   117 AYIMETFGPFMAFIRLW--IECMIVRPCSQA---------IVALTFSTYVLKPF--FPECTPPED 168
            .|...|.|...|||..|  |...::...|.|         ::|...||: .|.|  ||      |
Zfish   151 VYSYVTVGEIWAFITGWNLILSYVIGTASVARAWSATFDSLLAQKISTF-FKAFMSFP------D 208

  Fly   169 SARLL-------AVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYF 226
            :..:|       |:..:::||.:..:.|..:..|..|||...|:.|..:|.:|..:   |:|..:
Zfish   209 TQNVLAKYPDVFALILVMLLTGLLAFGVSESALVNKIFTGINLVVLTFVIISGFVK---GDTANW 270

  Fly   227 TFENTD----TKVT---SIALSFYSG-----------------LFAYNGWNYLNFIIEELKDPVK 267
            .....|    |.:|   .|...|.||                 .:|:.|::.:....||.|:|::
Zfish   271 NLTVEDYINRTNITGAQKIEKEFGSGGFAPFGLNGVLSGAATCFYAFVGFDCIATTSEEAKNPMR 335

  Fly   268 NLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFGMLAW-------TIPVF 325
            ::|..|..|..:....|...:.:. |::.|..::...:.    ..:||..:.|       ::...
Zfish   336 SIPIGIVASLLICFFAYFGVSAAL-TLMMPYYMLDKHSP----LPQAFDYVGWGPARYIVSVGSL 395

  Fly   326 VALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFA 390
            .||||  ::.|.:....|:.||.|.:|.:...|:.:..:..||..|.|...:::.|...:.|:.|
Zfish   396 CALST--SLLGSMFPMPRVIYAMAEDGLLFRFLSRMHKKTKTPALATLVSGIVAALMAFLFDLDA 458

  Fly   391 LINYVGFATWLSIGVAVLCLPWLRWAQPN 419
            |::.:...|.|:..:..:|:..||: ||:
Zfish   459 LVDLMSIGTLLAYTLVAVCVLILRY-QPS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	102/453 (23%)
slc7a3b	XP_001342962.3	2A0303	57..665	CDD:273330	105/473 (22%)
slc7a3b	XP_001342962.3	AA_permease_C	613..663	CDD:290617
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940