Protein Alignment pHCl-2 and Gabrp

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_112291.1
• Gene: Gabrp / 81658
• RGDID: 620532
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 134/519 - (25%)
• Similarity: 224/519 - (43%)
• Gaps: 109/519 - (21%)

  Fly    19 AGVHLGDLQQNLAANGSVVVSPLNTTDAFSVSINLSQSTVNNCPSLKNAESMALMELLTRLTAPC 83
            |.|.|..|.|.:...|:            ..::.:|:|...:.|..:|            |||
  Rat     8 AFVCLNLLAQRMCIQGN------------QFNVEVSRSDKLSLPGFEN------------LTA-- 46

  Fly    84 RYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNR 148
            .|::.:.|   |..|:  |:.|.....|..:.::..|::.:|....|:.|:.||||.|..   |:
  Rat    47 GYNKFLRP---NFGGD--PVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEG---NK 103

  Fly   149 RQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQK 213
            ...:  ::.|.:.||||..::...:.|.:...:..:.|..::.|||||.:.|:..|:.|.|:..|
  Rat   104 SFTL--DARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSK 166

  Fly   214 FPFDEQKCKTTLESWMYNTTLVQLHWETDN-PVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSH 277
            :|.|.|.||..||||.|:...|:..|...| .|...:.|:|.:|.:  ..|...:.||.:.
  Rat   167 YPMDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTI--QQYFTLVTVSQQE---- 225

  Fly   278 GSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFIT 342
               .|||:.:.....|.|.|.|::::.::||..:|.:||||||:..:..||||.:|.||:||..|
  Rat   226 ---TGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLESVPARTCIGVTTVLSMTT 287

  Fly   343 LSLSQENNLMKVS-YVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTF 406
            |.:....:|...: ::...:|:..:|..|:||:|:|:|
  Rat   288 LMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYA--------------------------- 325

  Fly   407 VPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLS---REDSAISLDEQ 468
            |.|.            |::..|:.    |..||......:....||..|:|   |:.|..|::..
  Rat   326 VAHY------------SSLQQMAV----KDRGPAKDSEEVNITNIINSSISSFKRKISFASIEIS 374

  Fly   469 DET-----STSESSDSSK----EKPAQT---FATMTPKEVSLWIDRKMRFVFPLSFIVFNALFW 520
            .:.     .|.::||..|    ||..:.   |....|..|    ||..:.:|||.|::.|..:|
  Rat   375 GDNVNYSDLTMKASDKFKFVFREKIGRIIDYFTIQNPSNV----DRYSKLLFPLIFMLANVFYW 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	128/492 (26%)
Gabrp	NP_112291.1	LIC	43..437	CDD:273305	125/472 (26%)
		LGIC_ECD	60..241	CDD:355788	54/194 (28%)
		Cys-loop	159..174	CDD:349787	6/14 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900