Protein Alignment pHCl-2 and glrb

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001072255.1
• Gene: glrb / 779708
• XenbaseID: XB-GENE-1011734
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 143/502 - (28%)
• Similarity: 233/502 - (46%)
• Gaps: 82/502 - (16%)

  Fly    61 CPSLKNAESMALM------ELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDS 119
            |||..:||.:|.:      .:|.||..  .||..|.|   |..|  :|:|:....:|....::..
 Frog    39 CPSQLSAEDLARVPANSTSNILNRLLV--SYDPRVRP---NFKG--IPVDVVVNIFINSFGSIQE 96

  Fly   120 SDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK------KMLWVPHIFLTNEQASTVL 178
            :.:.:.|...|:.|:.||||.    |||   ...|...|.      |.||.|.:|..||:.:...
 Frog    97 TTMDYRVNIFLRQRWNDPRLK----LPN---DFRGSDALTVDPTMFKCLWKPDLFFANEKNANFH 154

  Fly   179 GTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDN 243
            ..:.::.|..|:.:|.||.|.||..||.|.::...||.|.|:||..|||:.|.|..::..|::.:
 Frog   155 DVTQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGD 219

  Fly   244 PVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPS 308
            ||..:| :.|.:::    :..|.|...|.:....|:  |.|:.:.....|.|:||:|::..:.|:
 Frog   220 PVQMEK-IALPQFD----IKTEDIEYGNCTKYYKGT--GYYTCVEVIFTLRRQVGFYMMGVYAPT 277

  Fly   309 IMIVTISWVSFWLQADQTPARTTLGCTTLLSFIT--LSLSQENNLMKVSYVTMSEVWFLVCTIFI 371
            ::||.:||:|||:..|.:.||..||..::||..:  .:|:||  |.|||||...:||.:.|.:|.
 Frog   278 LLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQE--LPKVSYVKAIDVWLIACLLFG 340

  Fly   372 FGSLVEFAFVNTIWRRNNDLQLKK---------------RTTKYIVKSTFVP-HLKKHRRHGYRR 420
            |.||||:|.|..:......::.:|               ...|..|..|..| |:
 Frog   341 FASLVEYAVVQVLLNSPKRIEAEKAKIAKAEQAEGKGANAAKKNTVNGTGTPIHI---------- 395

  Fly   421 TDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAIS--------LDEQDETSTSESS 477
              ||:. :......|.|...:.:.:.:..|:  |||.| |..:|        ::..:....|::.
 Frog   396 --STLQ-VGENRCKKVCTSKSDLRSNDFSIV--GSLPR-DFELSNYDCYGKPIEVNNGLGKSQAK 454

  Fly   478 DSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTLVY 524
            ::.|..||:.......|.:.|:    .|.:||..|:.||.::| |||
 Frog   455 NNKKPPPAKPVIPSEAKRIDLY----SRALFPFCFLFFNVIYW-LVY 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	140/498 (28%)
glrb	NP_001072255.1	LIC	38..496	CDD:273305	141/500 (28%)
		LGIC_ECD_GlyR_beta	79..265	CDD:349811	56/199 (28%)
		Cys-loop	183..197	CDD:349811	5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010