Protein Alignment pHCl-2 and gabrb3

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_021327485.1
• Gene: gabrb3 / 566922
• ZFINID: ZDB-GENE-101102-2
• Length: 532
• Species: Danio rerio
• Alignment Length: 436
• Identity: 113/436 - (25%)
• Similarity: 207/436 - (47%)
• Gaps: 57/436 - (13%)

  Fly   121 DLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDE 185
            ::.:|:....|..:.|.|||::....|    :..::.:...||||..:..|::.|.|.|.:.|:.
Zfish   113 NMDYTLTMYFQQYWRDKRLAYTGIPLN----LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNR 173

  Fly   186 LTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWE-TDNPVSFDK 249
            :..::|:||||...|:..|..|.|:.:::|.|||.|...:||:.|.|..::.:|: .:..|:...
Zfish   174 MIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWKGGETAVTGVS 238

  Fly   250 QLQLTEYNLIG-SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVT 313
            :::|.:::::. .|.:.::..|.          |.|..:|.:..|.|.:||:::..::|||:|..
Zfish   239 RIELPQFSIVDYKLVSRNVVFST----------GAYPRLSLSFKLKRNIGYFILQTYMPSILITI 293

  Fly   314 ISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEF 378
            :||||||:..|.:.||..||.||:|:..|::......|.|:.||...:::.:.|.:|:|.:|:|:
Zfish   294 LSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 358

  Fly   379 AFVNTIW----------------RRNNDLQLKKRTTKY----------IVKSTFVPHLKKHRRHG 417
            ||||.|:                :.|||      ..||          ..|.:.|....:.:.|.
Zfish   359 AFVNYIFFGRGPQMQKKLAEKAEKANND------RNKYDGNKSVQEGGNCKPSSVKQSNQVQGHR 417

  Fly   418 YRR-TDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAISLDEQDETSTSESSDSSK 481
            :.| .||..:.:.||.........|.:.|..:......|:..::|.|...:|.....|...::..
Zfish   418 HSRGVDSQGNILLTTLEIHNEVAGNEITTSVSEARNSTSMVFDNSGIQYRKQSTARHSMDRNAQS 482

  Fly   482 EKPAQTFATMTPK-------EVSLWIDRKMRFVFPLSFIVFNALFW 520
            :||.....:...|       :|:. |||..|.:||..|.:||.::|
Zfish   483 KKPRLRRRSSQLKIKIPDLTDVNA-IDRWSRIIFPAVFSLFNLIYW 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	113/436 (26%)
gabrb3	XP_021327485.1	LIC	61..530	CDD:273305	113/436 (26%)