Protein Alignment pHCl-2 and gabrb4

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_005173931.1
• Gene: gabrb4 / 566514
• ZFINID: ZDB-GENE-070424-211
• Length: 512
• Species: Danio rerio
• Alignment Length: 540
• Identity: 134/540 - (24%)
• Similarity: 242/540 - (44%)
• Gaps: 97/540 - (17%)

  Fly    30 LAANGSVVVSPLNTTDAFSVSINLSQSTVNNCPSLKNAESMALMELLTRLTAPCRYDRMVPPVVH 94
            |||...|..:..::|.  |..|:::::||:              :||.......|.|...|||:
Zfish    16 LAALSFVCFAQSSSTG--STGISVAKTTVD--------------KLLKGYDIRLRPDFGGPPVI- 63

  Fly    95 NKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK 159
                  |.|.|    .|..:.::...::.:|:....|..:.|.|||::....|    :..::.:.
Zfish    64 ------VGMSI----NIASIDSISEVNMDYTITMYFQQSWRDKRLAYAEMALN----LTLDNRVA 114

  Fly   160 KMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTT 224
            ..||:|..:..|::.|.:.|.:.|:.:..::|:||||...|:..|..|.|:.:::|.|||.|...
Zfish   115 DQLWLPDTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 179

  Fly   225 LESWMYNTTLVQLHWE-TDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIIS 288
            :||:.|.|..:...|: .||.|:...:|:|.:::::     |...||.|...:.||    |..:|
Zfish   180 IESYGYTTDDIVFFWQGGDNAVTGVDKLELPQFSIV-----ELRLVSREVRFTTGS----YPRLS 235

  Fly   289 FTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMK 353
            .:..:.|.:||:::..::|||:|..:||||||:..|.:.||..||.||:|:..|::......|.|
Zfish   236 LSFRIKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGVTTVLTMTTINTHLRETLPK 300

  Fly   354 VSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGY 418
            :.||...:|:.:.|.:|:|.:|:|:||||.::......|.||...:....:...|..::.|   .
Zfish   301 IPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFFGRGPQQQKKINERLNKANNERPRYEEKR---L 362

  Fly   419 RRTDSTMSTMSTTSMDK--------------------------TCGPNNTVITIETPIIIGGSLS 457
            |..||..:...:.::..                          |...||.|:    |..:|.|:|
Zfish   363 REQDSISAPFQSNTLRSYTQRRNLYLEEQRKVGVDAYGNILLTTLEMNNEVM----PSDVGSSVS 423

  Fly   458 -REDSAISLDEQ-------------------DETSTSESSDSSKEKPAQTFATMTPK--EVSLWI 500
             ..:|.:|.|..                   |.::....::....:.:.......|.  :||. |
Zfish   424 DSRNSVMSFDSSGVQFRKPMGSRDGFSHHSLDRSAMRSRANCRLRRRSSKLKLKIPNLTDVST-I 487

  Fly   501 DRKMRFVFPLSFIVFNALFW 520
            |:..|.:||::|..||.::|
Zfish   488 DKWSRIIFPITFGFFNLIYW 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	129/524 (25%)
gabrb4	XP_005173931.1	LIC	13..510	CDD:273305	134/540 (25%)