Protein Alignment pHCl-2 and gabrz

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001108214.2
• Gene: gabrz / 561738
• ZFINID: ZDB-GENE-080303-26
• Length: 447
• Species: Danio rerio
• Alignment Length: 472
• Identity: 130/472 - (27%)
• Similarity: 213/472 - (45%)
• Gaps: 93/472 - (19%)

  Fly    86 DRMVPPVV------HNK-------DGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDP 137
            :.::||.:      :||       :|   |:.:.....|..:..:...::.:|....|:.|:.|.
Zfish    28 EEILPPTIQKLMKGYNKYLRPFFGNG---PVTVGMSLDIASIDTISEINMDYTATIFLRQRWTDE 89

  Fly   138 RLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQ 202
            ||.|..   |:...:.|  .|.::||||..|:.:.:.|.:...:.::.|..|:||||||.:.|:.
Zfish    90 RLCFDG---NKSLSLDG--RLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGTVLYALRIT 149

  Fly   203 ATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDN-PVSFDKQLQLTEYNLIGSLYNES 266
            .|:.|.|:..|:|.|.|.|...||||.||...|..:|...| .||....|||.:|.|.....:||
Zfish   150 TTVACSMDLTKYPMDRQTCMLQLESWGYNVKDVVFYWTRGNQSVSGLDHLQLAQYTLEDHYTSES 214

  Fly   267 IRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTT 331
            ..|..         .|||..:.|...|.|.:.|::::.::||..:|.:||||||:.....|||..
Zfish   215 EAVYE---------TGNYPKLIFHFKLKRSILYFILETYVPSSALVVLSWVSFWISQSSVPARIC 270

  Fly   332 LGCTTLLSFITLSLSQENNLMKVS-YVTMSEVWFLVCTIFIFGSLVEFAFVN--TIWRRN----- 388
            :|.||:|:..||.:....:|...: ::...:|:..:|..||||:|:|:|..:  |:.:.|
Zfish   271 IGVTTVLTMTTLMMGARTSLPNANCFIKAIDVYLGICFSFIFGALIEYAVAHFCTLHQPNAANAY 335

  Fly   389 ---NDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPI 450
               .::|.::.....||.| |..|..:.|:.     :..:|.|.:.        ||     .||
Zfish   336 MYGQEMQEREDEMNGIVTS-FGSHALRARKR-----EEMLSRMGSV--------NN-----PTP- 380

  Fly   451 IIGGSLSREDSAISLDEQDETSTSESSDSSK-----------EKPAQTFATMTPKEVSLWIDRKM 504
                |.|:||.:.|   |.:|..::....::           |.|.             :||...
Zfish   381 ----SESKEDVSSS---QPQTRCTKCMSRARRIIRCLYCCKVENPH-------------YIDNYS 425

  Fly   505 RFVFPLSFIVFNALFWT 521
            |..|||||::.|.|:||
Zfish   426 RLTFPLSFVIINLLYWT 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	130/472 (28%)
gabrz	NP_001108214.2	LIC	26..444	CDD:273305	130/472 (28%)
		LGIC_ECD_GABAAR_pi	54..235	CDD:349805	59/194 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810