Protein Alignment pHCl-2 and gabra6b

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 515
• Identity: 135/515 - (26%)
• Similarity: 213/515 - (41%)
• Gaps: 111/515 - (21%)

  Fly    30 LAANGSVVVSPLNTTDAFSVSINLSQSTVNNCPSLKNAESMALMELLTRLTAPCRYD-RMVP--- 90
            |:..|.||.:|...|..:                |.|     :..:|.||..  .|| |:.|
Zfish    10 LSCVGQVVANPPTETRIY----------------LDN-----ITRILDRLLD--GYDNRLRPGFG 51

  Fly    91 -PVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMG 154
             ||.      ||..||:...:    ..:...::::|:....:..::|.||.|.           |
Zfish    52 GPVT------EVKTDIFVTSF----GPVSDVEMEYTMDVFFRQTWIDDRLKFE-----------G 95

  Fly   155 ESELKKM-------LWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQ 212
            ..|:.::       :|.|..|..|.:.|.....:..::|..|..|||:|.:.||.....|.|...
Zfish    96 PIEILRLNNLMVSKIWTPDTFFRNGKRSISHNMTTPNKLFRIMQNGTILYTMRLTINAECPMRLI 160

  Fly   213 KFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFD---KQLQLTEYNLIGSLYNESIRVSNESY 274
            .||.|...|.....|:.|..:.:...|:.....|.:   :...|.:|:|||.      .||:|..
Zfish   161 NFPMDGHSCPLKFGSYAYPMSEIVYTWKKGPLFSVEVPQESSSLLQYDLIGQ------TVSSERL 219

  Fly   275 MSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLS 339
            .|:   .|.|.:::....|.|::|:::|..::|.||.|.::.||||:..:..||||..|.||:|:
Zfish   220 KSN---TGEYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVFGITTVLT 281

  Fly   340 FITLSLSQENNLMKVSYVTMSEVWFL-VCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVK 403
            ..|||:|..::|.||||.|..: ||: ||..|:|.:|:|||.||..    :.||..|..
Zfish   282 MTTLSISARHSLPKVSYATAMD-WFIAVCFAFVFSALIEFAAVNYF----STLQANKEL------ 335

  Fly   404 STFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAIS---- 464
                      ||....|..:..:...:....           :..|:..||.|.:..:::|
Zfish   336 ----------RRANIARAAAAAAAARSDGEG-----------VLNPLDPGGVLKKRMNSLSQRSA 379

  Fly   465 LDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTLVY 524
            .|.....|.|:........||......|    |: ||:..|.:|||||..||.::| :||
Zfish   380 TDRFSRPSQSDFHQQGSAVPANNMLIGT----SI-IDKYSRILFPLSFGAFNLVYW-IVY 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	127/495 (26%)
gabra6b	XP_002667403.3	Neur_chan_LBD	32..239	CDD:280998	56/238 (24%)
		LIC	33..433	CDD:273305	125/469 (27%)
		Neur_chan_memb	246..430	CDD:280999	66/220 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900