Protein Alignment pHCl-2 and gabrb2a

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001019558.2
• Gene: gabrb2a / 336252
• ZFINID: ZDB-GENE-030131-8196
• Length: 519
• Species: Danio rerio
• Alignment Length: 526
• Identity: 123/526 - (23%)
• Similarity: 239/526 - (45%)
• Gaps: 91/526 - (17%)

  Fly    61 CP---------SLKNAESMALM-ELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMK 115
            ||         |:::..:|.:: :.:.||..  .||..:.|     |....|:.:.....|..:.
Zfish    14 CPLIVAVACAQSIRDPSNMPVVKDTVDRLMK--GYDIRLRP-----DFGGAPVAVGMNIDIASID 71

  Fly   116 NLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGT 180
            .:...::.:|:....|..:.|.||::|....|    :..::.:...||||..:..|::.|.|.|.
Zfish    72 MVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLN----LTLDNRVADQLWVPDTYFLNDKKSFVHGV 132

  Fly   181 SAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWE-TDNP 244
            :.|:.:..::|:||||...|:..|..|.|:.:::|.|||.|...:||:.|.|..::.:|. .|..
Zfish   133 TVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDGA 197

  Fly   245 VSFDKQLQLTEYNLIG-SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPS 308
            ||..::::|.:::::. .|.::::..|.          |:|..:|.:..|.|.:||:::..::||
Zfish   198 VSGVERIELPQFSIVDYKLISKNVVFST----------GSYPRLSLSFKLKRNIGYFILQTYMPS 252

  Fly   309 IMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFG 373
            |:|..:||||||:..|.:.||..||.||:|:..|::......|.|:.||...:::.:.|.:|:|.
Zfish   253 ILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFL 317

  Fly   374 SLVEFAFVNTIW----------------RRNNDLQLKKRTTKYIVKS------TFVPHLKKHRRH 416
            :|:|:||||.|:                ..||: :|:....|::|.|      .....:|:....
Zfish   318 ALLEYAFVNYIFFGRGPQRQKKAAEKAATANNE-KLRPDPNKWLVGSVVQRDDALYARMKQREID 381

  Fly   417 GY------------------RRTDSTMS--TMSTTSMDKTCGPN----------NTVITIETPII 451
            ||                  :|...|..  .::|..|....||:          :|::..::..:
Zfish   382 GYDSMWDPIFAEDAALGLGDQRLKMTPDDIRLTTVEMKNEMGPSDLSRGLGDPRSTMLAYDSSTL 446

  Fly   452 --IGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIV 514
              ...:::|::...|..|:..|   :.....:.:.:|....:........||:..|.:||..|..
Zfish   447 QYRRAAMARQNYGHSALERHAT---QKKSRLRRRASQLKVNIPDLSDVNSIDKWSRMIFPTLFSF 508

  Fly   515 FNALFW 520
            ||.::|
Zfish   509 FNIVYW 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	123/526 (23%)
gabrb2a	NP_001019558.2	LIC	7..517	CDD:273305	123/526 (23%)