Protein Alignment pHCl-2 and Gabrr3

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001074659.1
• Gene: Gabrr3 / 328699
• MGIID: 3588203
• Length: 464
• Species: Mus musculus
• Alignment Length: 477
• Identity: 124/477 - (25%)
• Similarity: 213/477 - (44%)
• Gaps: 98/477 - (20%)

  Fly    76 LTRLTAPCRYDRMVPPVVHNKD----------GEEVPMDIYARFYIYVMKNLDS---SDLQFTVQ 127
            ||::..|.|     ..::|.:|          |..||:.|..:     ::::||   .::.||:.
Mouse    50 LTKVWHPKR-----EQLLHIEDHDFSTRPGFGGSPVPVGIDVQ-----VESIDSISEVNMDFTMT 104

  Fly   128 GLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPN 192
            ..|:..:.|.||:|.|   ...:.:..:..|.:.:|||.||..:.:.|.:..|:.::.:..::|:
Mouse   105 FYLRHYWKDERLSFPS---TTNKSMTFDRRLLQKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPD 166

  Fly   193 GTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYN 257
            |.||.|.|:..:..|:|:|.:||.|.|.|...|||:.||...:.|:|:..|     |.|...|..
Mouse   167 GNVLFSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEEDLMLYWKHGN-----KSLNTEERI 226

  Fly   258 LIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQ 322
            .:...:.|....|  |.::..|..|.|..:....:|.|.|.::|:..:.|::::|.:||||||:.
Mouse   227 SLSQFFIEEFSAS--SGLAFYSSTGWYYRLFINFVLRRHVFFFVLQTYFPAMLMVMLSWVSFWID 289

  Fly   323 ADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTI--- 384
            ....|||.:||.||:|:..|:......::.:||||...:|:..|.::|:|.|::|:|.||.:
Mouse   290 RRAVPARVSLGITTVLTMSTVVTGVSASMPQVSYVKAVDVYMWVSSLFVFLSVIEYATVNYLTTV 354

  Fly   385 --WRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTM-------STTSMDKTCGPN 440
              |::.|                     ::.:..|....|:..:..       |.|.:|:|
Mouse   355 EEWKQLN---------------------RRGKISGMYHIDAVQAMAFDGCYHDSETDVDQT---- 394

  Fly   441 NTVITIETPIIIGGSLSREDSAISL-DEQDETST----SESSDSS--KEKPAQTFATMTPKEVSL 498
                                 :.|| .|:|..||    |..:|||  |.|...........|.:.
Mouse   395 ---------------------SFSLHSEEDSMSTKFTGSPCADSSQIKRKSLGGNVGRIILENNH 438

  Fly   499 WIDRKMRFVFPLSFIVFNALFW 520
            .||...|.|||..:|:||..:|
Mouse   439 VIDTYSRIVFPTVYIIFNLFYW 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	124/477 (26%)
Gabrr3	NP_001074659.1	LIC	58..463	CDD:273305	121/469 (26%)
		Neur_chan_LBD	59..264	CDD:280998	57/219 (26%)
		Neur_chan_memb	271..460	CDD:280999	60/234 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810