Protein Alignment pHCl-2 and Gabrg2

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001380704.1
• Gene: Gabrg2 / 29709
• RGDID: 61966
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 129/531 - (24%)
• Similarity: 219/531 - (41%)
• Gaps: 98/531 - (18%)

  Fly     3 TLGIFVLIS-YLGLSSAAGVHLGDLQQNLAANGSVVVSPLNTTDAFSVSINLSQSTVNNCPSLKN 66
            ||.|.:|:| |.|.:|...   .|..::.|:|.:.|::|.......:|.:|
  Rat    23 TLWILLLLSLYPGFTSQKS---DDDYEDYASNKTWVLTPKVPEGDVTVILN-------------- 70

  Fly    67 AESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQ 131
                .|:|         .||..:.|.:..|     |..|:...|:..:..:::.::::|:.....
  Rat    71 ----NLLE---------GYDNKLRPDIGVK-----PTLIHTDMYVNSIGPVNAINMEYTIDIFFA 117

  Fly   132 LRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVL 196
            ..:.|.||.|:|.:...|.    .|.:...:|:|..|..|.:.:.....:..:.:..|:.:|.||
  Rat   118 QTWYDRRLKFNSTIKVLRL----NSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVL 178

  Fly   197 TSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDN-PVSFDKQLQLTEYNLIG 260
            .:.||.....|.:....||.||..|.....|:.|....:...|:..: .|...:..:|.:::.:|
  Rat   179 YTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVG 243

  Fly   261 SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQ 325
             |.|.:..|...|        |:|.::|....|:|.:||:.|..::|..:||.:||||||:..|.
  Rat   244 -LRNTTEVVKTTS--------GDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA 299

  Fly   326 TPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNND 390
            .||||:||.||:|:..|||.....:|.||||||..:::..||.||:|.:|||:.
  Rat   300 VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYG----------- 353

  Fly   391 LQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGS 455
                  |..|     ||.:.|..:....::.:..:...|..:......|.:..|.:
  Rat   354 ------TLHY-----FVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQM--------- 398

  Fly   456 LSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLW-----------IDRKMRFVFP 509
                ::|..|.|:||....|..|.  :..|..|..........|           :|...|..||
  Rat   399 ----NNATHLQERDEEYGYECLDG--KDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFP 457

  Fly   510 LSFIVFNALFW 520
            .:|.:||.::|
  Rat   458 TAFCLFNLVYW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	116/487 (24%)
Gabrg2	NP_001380704.1	LIC	68..471	CDD:273305	115/483 (24%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	40/193 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900