Protein Alignment pHCl-2 and Gabrr2

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_038965308.1
• Gene: Gabrr2 / 29695
• RGDID: 61902
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 457
• Identity: 123/457 - (26%)
• Similarity: 211/457 - (46%)
• Gaps: 99/457 - (21%)

  Fly    98 GEEVPMDIYARFYIYVMKNLDS---SDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK 159
            |..:|:.:..:     :::|||   .|:.||:...|:..:.|.||||.| ..||.....|  .|.
  Rat   100 GPAIPVGVDVQ-----VESLDSISEVDMDFTMTLYLRHYWRDERLAFPS-SSNRSMTFDG--RLV 156

  Fly   160 KMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTT 224
            |.:|||.:|..:.:.|....|:..:.:..::|:|.||.|.|:..|..|.|:|..||.|.|.|...
  Rat   157 KKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLE 221

  Fly   225 LESWMYNTTLVQLHWET-DNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIIS 288
            |||:.|....:.|:|:. |..:..|:::.|::: ||...:..| |::  .|.|.|.....|  |:
  Rat   222 LESYAYTDEDLMLYWKNGDESLKTDEKISLSQF-LIQKFHTTS-RLA--FYSSTGWYNRLY--IN 280

  Fly   289 FTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMK 353
            ||  |.|.:.::::..:.|:.::|.:||||||:.....|||.:||..|:|:..|:......::.:
  Rat   281 FT--LRRHIFFFLLQTYFPATLMVMLSWVSFWIDHRAVPARVSLGIMTVLTMSTIITGVNASMPR 343

  Fly   354 VSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGY 418
            |||:...:::..|..:|:|.|::|:|.||.:                    |.|...|:.:..
  Rat   344 VSYIRAVDIYLWVSFVFVFLSVLEYAAVNYL--------------------TTVQEQKERKLR-- 386

  Fly   419 RRTDSTMSTMSTTSMDK---TCGP-NNTVITIETPIIIGGSLSREDSAISL------------DE 467
                           ||   |||. ::..:|::      ||.| |..|.||            :.
  Rat   387 ---------------DKFPCTCGMLHSRTMTLD------GSYS-ESEANSLAGYPRSHILPEEER 429

  Fly   468 QDE-----TSTSESSDSSKEKPAQTFATMTPKEVSLW-------IDRKMRFVFPLSFIVFNALFW 520
            ||:     ...||.:.|.|:       .:...::.|:       ||:..|.:||..:||||.::|
  Rat   430 QDKIVVHLALNSELTSSRKK-------GLLKGQMGLYIFQNTHAIDKYSRLIFPAFYIVFNLIYW 487

  Fly   521 TL 522
            ::
  Rat   488 SV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	123/455 (27%)
Gabrr2	XP_038965308.1	LIC	87..490	CDD:455710	123/457 (27%)
		LGIC_ECD_GABAAR_rho	102..287	CDD:349806	62/200 (31%)
		Cys-loop	204..218	CDD:349806	7/13 (54%)