Protein Alignment pHCl-2 and GABRD

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_016856425.1
• Gene: GABRD / 2563
• HGNCID: 4084
• Length: 687
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 106/434 - (24%)
• Similarity: 206/434 - (47%)
• Gaps: 64/434 - (14%)

  Fly   102 PMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMG-ESELKKMLWVP 165
            |:::.....:..:.::..:::::|:...|...:.|.||::     |.....:| :|.....||:|
Human   298 PVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY-----NHTNETLGLDSRFVDKLWLP 357

  Fly   166 HIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMY 230
            ..|:.|.:::.....:.:::|..:.|:|.:|.|.|:.:|:.|.|:..|:|.|||:|...|||:.|
Human   358 DTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGY 422

  Fly   231 NTTLVQLHW-ETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLT 294
            ::..:..:| |:...:....:|||.::.:      .|.|.:.|  :.:....|.:..:|....|.
Human   423 SSEDIVYYWSESQEHIHGLDKLQLAQFTI------TSYRFTTE--LMNFKSAGQFPRLSLHFHLR 479

  Fly   295 REVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTM 359
            |..|.|:|..::||:::|.:||||||:.....|||.:||.||:|:..||.:|..::|.:.|.:..
Human   480 RNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKA 544

  Fly   360 SEVWFLVCTIFIFGSLVEFAFV--NTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTD 422
            .:|:|.:|.:|:|.:|||:||.  |..:|:....::|               :.:.|.....|..
Human   545 LDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVK---------------VSRPRAEMDVRNA 594

  Fly   423 STMSTMSTTSMDKTCGPNNTVITIETPII-----IGGSLSREDSAISLDEQDETSTSESSDSSKE 482
            ..:.::|...           :|.|..|.     :.|:|.....::.:         |:.::.||
Human   595 IVLFSLSAAG-----------VTQELAISRRQRRVPGNLMGSYRSVGV---------ETGETKKE 639

  Fly   483 KPAQT------FATMTPKEVSLWIDRKMRFVFPLSFIVFNALFW 520
            ..|::      .|.:.|.:... ||...|.|||.:|...|.::|
Human   640 GAARSGGQGGIRARLRPIDADT-IDIYARAVFPAAFAAVNVIYW 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	106/434 (24%)
GABRD	XP_016856425.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810