Protein Alignment pHCl-2 and Gabrb1

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_037088.1
• Gene: Gabrb1 / 25450
• RGDID: 2649
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 115/533 - (21%)
• Similarity: 216/533 - (40%)
• Gaps: 141/533 - (26%)

  Fly    63 SLKNAESMALMELLTRLTAPC-----------------------RYDRMVPPVVHNKDGEEVPMD 104
            :::|.||:.|:.....:...|                       .||..:.|     |....|:|
  Rat     3 TVQNRESLGLLSFPVMVAMVCCAHSSNEPSNMSYVKETVDRLLKGYDIRLRP-----DFGGPPVD 62

  Fly   105 IYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFL 169
            :..|..:..:..:...::.:|:....|..:.|.||::|....|    :..::.:...||||..:.
  Rat    63 VGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLN----LTLDNRVADQLWVPDTYF 123

  Fly   170 TNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTL 234
            .|::.|.|.|.:.|:.:..::|:||||...|:..|..|.|:.:::|.|||.|...:||:.|.|..
  Rat   124 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 188

  Fly   235 VQLHWE-TDNPVSFDKQLQLTEYNLIG-SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREV 297
            ::.:|. .:..|:...:::|.:::::. .:.::.:..:.          |.|..:|.:..|.|.:
  Rat   189 IEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTT----------GAYPRLSLSFRLKRNI 243

  Fly   298 GYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEV 362
            ||:::..::||.:|..:||||||:..|.:.||..||.||:|:..|:|......|.|:.||...::
  Rat   244 GYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDI 308

  Fly   363 WFLVCTIFIFGSLVEFAFVNTIW-----------------RRNNDLQLKK--------------- 395
            :.:.|.:|:|.:|:|:||||.|:                 ...|.|::.|
  Rat   309 YLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLE 373

  Fly   396 -----------------RTTKYIVKSTFVPHLKK-HRRHGYRRTDSTMSTMSTTSMDKTCGPNNT 442
                             :.|.|...|..:.:.|. ..|.|:.|           .:|:...|..
  Rat   374 IRNETSGSEVLTGVSDPKATMYSYDSASIQYRKPLSSREGFGR-----------GLDRHGVPGK- 426

  Fly   443 VITIETPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFV 507
                       |.:.|..|.:.:...|.|..:.                        ||:..|..
  Rat   427 -----------GRIRRRASQLKVKIPDLTDVNS------------------------IDKWSRMF 456

  Fly   508 FPLSFIVFNALFW 520
            ||::|.:||.::|
  Rat   457 FPITFSLFNVVYW 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	115/533 (22%)
Gabrb1	NP_037088.1	LIC	9..472	CDD:273305	113/527 (21%)