Protein Alignment pHCl-2 and Glra2

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001344028.1
• Gene: Glra2 / 237213
• MGIID: 95748
• Length: 452
• Species: Mus musculus
• Alignment Length: 473
• Identity: 131/473 - (27%)
• Similarity: 205/473 - (43%)
• Gaps: 86/473 - (18%)

  Fly    62 PSLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTV 126
            ||...:.|..|.:|:.|.:.   ||..:.|   |..|.  |:::....:|....::..:.:.:.|
Mouse    38 PSQTLSPSDFLDKLMGRTSG---YDARIRP---NFKGP--PVNVTCNIFINSFGSVTETTMDYRV 94

  Fly   127 QGLLQLRYLDPRLAFSSYLPNRR---QPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTS 188
            ...|:.::.|.|||:|.| |:..   .|.|.:|     :|.|.:|..||:.:.....:..::|..
Mouse    95 NIFLRQQWNDSRLAYSEY-PDDSLDLDPSMLDS-----IWKPDLFFANEKGANFHDVTTDNKLLR 153

  Fly   189 IYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQL 253
            |..||.||.|.||..||.|.|:.:.||.|.|.|...|||:.|....:...|.:|.||...:.|.|
Mouse   154 ISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTL 218

  Fly   254 TEYNLIGSLYNESIRVSNE-SYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWV 317
            .::.|         :...| .|.:.....|.::.|.....|.|::|||:|..::||::||.:|||
Mouse   219 PQFIL---------KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274

  Fly   318 SFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVN 382
            |||:..|..|||..||.||:|:..|.|.....:|.|||||...::|..||.:|:|.:|:|:|.||
Mouse   275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVN 339

  Fly   383 TIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIE 447
            .:.|::.:....:|..|...|...|....:....||.
Mouse   340 FVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYG---------------------------- 376

  Fly   448 TPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSL----WIDRKMRF-- 506
                :|..|..:|..                :.|..||... ...||:...    ::||..|.
Mouse   377 ----MGHCLQMKDGT----------------AVKATPANPL-PQPPKDADAIKKKFVDRAKRIDT 420

  Fly   507 ----VFPLSFIVFNALFW 520
                .|||:|::||..:|
Mouse   421 ISRAAFPLAFLIFNIFYW 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	131/473 (28%)
Glra2	NP_001344028.1	LIC	46..441	CDD:273305	128/465 (28%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	236..241		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910