Protein Alignment pHCl-2 and Gabrr3

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_620252.1
• Gene: Gabrr3 / 192258
• RGDID: 621564
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 428
• Identity: 115/428 - (26%)
• Similarity: 201/428 - (46%)
• Gaps: 49/428 - (11%)

  Fly    98 GEEVPMDIYARFYIYVMKNLDS---SDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK 159
            |..||:.|..:     ::::||   .::.||:...|:..:.|.||:|.|   ...:.:..:..|.
  Rat    77 GSPVPVGIDVQ-----VESIDSISEVNMDFTMTFYLRHYWKDERLSFPS---TTNKSMTFDRRLI 133

  Fly   160 KMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTT 224
            :.:|||.||..:.:.|.:..|:.::.:..::|:|.||.|.|:..:..|:|:|.:||.|.|.|...
  Rat   134 QKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRFPLDTQNCSLE 198

  Fly   225 LESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISF 289
            |||:.||...:.|:|:..|     |.|...|:..:...:.|....|  |.::..|..|.|..:..
  Rat   199 LESYAYNEEDLMLYWKHGN-----KSLNTEEHISLSQFFIEEFSAS--SGLAFYSSTGWYYRLFI 256

  Fly   290 TVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKV 354
            ..:|.|.:.::|:..:.|::::|.:||||||:.....|||.:||.||:|:..|:......::.:|
  Rat   257 NFVLRRHIFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIVTGVSASMPQV 321

  Fly   355 SYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYR 419
            |||...:|:..|.::|:|.|::|:|.||.:                    |.|...|:..|.|..
  Rat   322 SYVKAVDVYMWVSSLFVFLSVIEYAAVNYL--------------------TTVEEWKQLNRRGKI 366

  Fly   420 RTDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAISLDEQDETSTSESSDSS--KE 482
            .....:..:...:.| .|..:......:|...:.   |.|||.     :.:.:.|..:|||  |.
  Rat   367 SGMYNIDAVQAMAFD-GCYHDGETDVDQTSFFLH---SEEDSM-----RTKFTGSPCADSSQIKR 422

  Fly   483 KPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFW 520
            |...........|.:..||...|.|||:.:|:||..:|
  Rat   423 KSLGGNVGRIILENNHVIDTYSRIVFPVVYIIFNLFYW 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	115/428 (27%)
Gabrr3	NP_620252.1	LIC	58..463	CDD:273305	115/428 (27%)
		LGIC_ECD	79..264	CDD:355788	54/199 (27%)
		Cys-loop	181..195	CDD:349787	7/13 (54%)
		Interaction with SQSTM1. /evidence=ECO:0000269|PubMed:12431995	344..445		25/129 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810