Protein Alignment pHCl-2 and glra4b

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001189440.1
• Gene: glra4b / 192125
• ZFINID: ZDB-GENE-020402-2
• Length: 492
• Species: Danio rerio
• Alignment Length: 486
• Identity: 140/486 - (28%)
• Similarity: 222/486 - (45%)
• Gaps: 71/486 - (14%)

  Fly    62 PSLKNAESMALMELLTRLTAPCR-YDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFT 125
            ||:: .:.|:..:.|.:|..... ||..:.|   |..|.  |:::....:|....::..:.:.:.
Zfish    34 PSVR-TKPMSPSDFLDKLMGKTSGYDARIRP---NFKGP--PVNVTCNIFINSFGSITETTMDYR 92

  Fly   126 VQGLLQLRYLDPRLAFSSYLPNRR---QPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELT 187
            :...|:.::.|||||:..| |:..   .|.|.:|     :|.|.:|..||:.:.....:..::|.
Zfish    93 LNVFLRQQWNDPRLAYKEY-PDDSLDLDPSMLDS-----IWKPDLFFANEKGANFHEVTTDNKLL 151

  Fly   188 SIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQ 252
            .|:.||.||.|.||...|.|.|:.:.||.|.|.|...|||:.|....:...|..:.||.....|.
Zfish   152 RIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLM 216

  Fly   253 LTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWV 317
            |.::.|     .|.   .:..|.:.....|.::.|.....|.|::|||:|..::||::.|.:|||
Zfish   217 LPQFVL-----KEE---KDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWV 273

  Fly   318 SFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVN 382
            |||:..|..|||..||.||:|:..|.|.....:|.|||||...::|..||.:|:|.:|:|:|.||
Zfish   274 SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVN 338

  Fly   383 TIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIE 447
            .:.|:              .|..|  .|::..|...|...::....:..:.:|:   ||  :|..
Zfish   339 FVSRQ--------------YKEFF--RLRRKLRQEQRNRAASGQAGAAETKNKS---NN--VTGG 382

  Fly   448 TPIIIGGSLSREDSAISLDEQDET------------STSESSDSSKEKPAQTFATMTP------- 493
            ||   ..:..|:.||.:.:||..:            .||.|.|....:.|..||.:.|
Zfish   383 TP---SRNAQRQCSACAREEQLASQNQDLYFPGFGIDTSLSGDGPLSEAAAMFAGLPPGHALFDI 444

  Fly   494 ----KEVSLWIDRKMRFVFPLSFIVFNALFW 520
                .|.:..||...|.||||||:|||..:|
Zfish   445 RRRFVEQAKRIDTISRAVFPLSFLVFNVFYW 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	140/486 (29%)
glra4b	NP_001189440.1	LIC	5..478	CDD:273305	140/486 (29%)
		Neur_chan_LBD	47..253	CDD:280998	58/224 (26%)
		Neur_chan_memb	260..475	CDD:280999	74/238 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910