Protein Alignment pHCl-2 and lgc-58

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001368738.1
• Gene: lgc-58 / 191637
• WormBaseID: WBGene00001587
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 138/574 - (24%)
• Similarity: 235/574 - (40%)
• Gaps: 145/574 - (25%)

  Fly    60 NCPSLKNAESMALMELLTRLTAPCR--YDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDL 122
            |.|.::.:.|..:...|..|....|  ||...|||.|:|  |||.: :....||..|.:..:..:
 Worm    14 NSPKVEASRSEPVPIYLDNLLNAGRQVYDNQSPPVQHDK--EEVTV-VELAMYIEGMSSFRTQTM 75

  Fly   123 QFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELT 187
            .|.:....|..:.|||||.:.   .||..:..::.|.|| |.|.::..|.:.:.....:..:.|.
 Worm    76 DFQLDVYFQQFWRDPRLAHNE---TRRVLVKDKAVLHKM-WKPDVYFANARIAEFHEVTQPNFLV 136

  Fly   188 SIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQ 252
            .|.|:|::|..||:...:.|.:|.:|:|.|.|:|...:.|:.|.|..:.:.|:.|.|::.:..:.
 Worm   137 WIQPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQLVIKWKEDEPITRNPNIA 201

  Fly   253 LTEYNLIGSLYNESIRVSNESYMSHGSLEGNY-----SIISFTVLLTREVGYYVIDYFLPSIMIV 312
            :::.::: .||             .|..:|||     |.::....:.||:.::|:..::|:.:||
 Worm   202 MSDMHIV-DLY-------------PGLCDGNYSTGTWSCVTAEFFVKREITHHVMQSYVPTTLIV 252

  Fly   313 TISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVE 377
            .|||.||||..:..|||.:|..||||:..|.:.:....|.:|||:...:||...|.:|:||.::|
 Worm   253 VISWFSFWLDVEAVPARVSLAITTLLTLSTQANAARMALPEVSYMKAIDVWMGACMMFVFGVMIE 317

  Fly   378 FAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKK--------------HRRHGYRRT------- 421
            |..||...|:.....   ||...||.::.:..:|.              |.||.:.|.
 Worm   318 FTIVNYAQRQGRKWH---RTDAEIVMASSLESVKSGNAEKKPSRGDLGAHARHLFLRLRTNERQH 379

  Fly   422 ----------------DSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAISLD---E 467
                            |:.....|.:..|:...|     .::.|       ..||:....:   |
 Worm   380 LVEDPPEQIAMNDTAYDTVSQAYSNSFSDEEAAP-----VVQPP-------QNEDAEAQEEVWAE 432

  Fly   468 QDETSTSE---------------------------------------------SSDSSKEKP--- 484
            |.||:.||                                             .:|||::|.
 Worm   433 QKETNLSEVWKESDPAERLAHWNEKENDASSPLMGNGRAHVRYGAAEKMKNRKCNDSSRKKEKWS 497

  Fly   485 ------------AQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTLVYCL 526
                        ...|..:..:..:..||:..|::|||:||:||..:|  :|.|
 Worm   498 SAIKQIQKHKRNGSVFGKIAGRNRAKKIDQTSRWIFPLTFIIFNLTYW--IYYL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	136/568 (24%)
lgc-58	NP_001368738.1	LIC	30..548	CDD:273305	133/555 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010