Protein Alignment pHCl-2 and lgc-52

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_502839.3
• Gene: lgc-52 / 190669
• WormBaseID: WBGene00013517
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 111/463 - (23%)
• Similarity: 192/463 - (41%)
• Gaps: 96/463 - (20%)

  Fly    63 SLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQ 127
            ||..|::..|..:|.     ..|.|...|       |..|:.:.....|..:.::.:....||:.
 Worm    39 SLSGAKATDLARILM-----TNYSRNALP-------EPAPVKVEVEITIQDISDISAITGTFTID 91

  Fly   128 GLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPN 192
            ..:...:.|.|||||...|.|:. :..:.:::..||.|::.:.|.:::.|..:...:.|..|:||
 Worm    92 YWISAIWNDKRLAFSHLDPCRKN-LSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPN 155

  Fly   193 GTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYN 257
            ||:..:.|:::...|.||.:.||.|..:|....||:.||...|:|.|...:|||..:    .:||
 Worm   156 GTIWLNYRIRSEAPCQMNLRNFPLDSIRCSLVFESYSYNAADVELQWLEWSPVSTVR----NDYN 216

  Fly   258 LIGSLYNESIRVSNESYMSHGSLEGNYSI-----ISFTVLLTREVGYYVIDYFLPSIMIVTISWV 317
            |      ...|::|.:|   ||:...|:.     :|.::...|..|:|::..:||:.:.|.|||:
 Worm   217 L------PDFRMTNITY---GSVTEAYTAGMWHRLSVSIHFERLYGFYILQMYLPTYISVFISWI 272

  Fly   318 SFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVN 382
            :||:.....|||.||..::|::......:...:|.|.|||...::|...|..|||.||:|.|.|
 Worm   273 AFWMDTKALPARITLSVSSLMALTFQFGNIVKSLPKASYVKAIDIWMFSCVGFIFFSLIELAIV- 336

  Fly   383 TIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIE 447
                ..||                       :.|..|..:...|.
 Worm   337 ----AYND-----------------------KMHDQRLREVRCSV-------------------- 354

  Fly   448 TPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSF 512
                  |:|:..    .:.:.:.|:.....:.|..:...:       |:...|||....:||..|
 Worm   355 ------GNLNSN----GIGQYNSTTRRSFVELSARRAKGS-------ELGASIDRVASMLFPTMF 402

  Fly   513 IVFNALFW 520
            .:||.::|
 Worm   403 ALFNLVYW 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	111/463 (24%)
lgc-52	NP_502839.3	Neur_chan_LBD	45..248	CDD:280998	57/228 (25%)
		LIC	52..413	CDD:273305	107/450 (24%)
		Neur_chan_memb	259..>338	CDD:280999	29/83 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1260459at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820