Protein Alignment pHCl-2 and lgc-42

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_497489.3
• Gene: lgc-42 / 189722
• WormBaseID: WBGene00021437
• Length: 412
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 106/467 - (22%)
• Similarity: 199/467 - (42%)
• Gaps: 91/467 - (19%)

  Fly    72 LMELLTRLTAPCR------YDRMVPPVVHNKDGE-EVPMDIYARFYIYVMKNLDSSDLQFTVQGL 129
            |..||.|:|...|      .|:.:|     ::|. :.|:.::..||:..:.|..::::.:.:...
 Worm     8 LFFLLLRITLANRDVFRLLQDKPMP-----RNGNPKAPLQVHFGFYVESLGNFRATEMTYDMDMY 67

  Fly   130 LQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGT 194
            |.:.:.|..:..:    .....::.:.::...:|:|.::..|.:.:.....:..:....|.|.||
 Worm    68 LYMSWQDDSMRHN----ETEHVLVNDKDILDKIWLPDLYFANARTAYFHKVTVHNFNMFISPQGT 128

  Fly   195 VLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLI 259
            :...||:...|.|.::.:.:|.|.|.|...:.|:.:....:.:.|..::|:.|:.::.|.|::
 Worm   129 ISYGTRVTLNLACNLDLKDYPLDYQTCYIKVISYAHVKNEMNVSWFPNDPIRFNPEIDLPEFH-- 191

  Fly   260 GSLYNESIRVSNESY--------MSHGSLE-GNYSIISFTVLLTREVGYYVIDYFLPSIMIVTIS 315
                   ||..::.|        ::|.|.. |.:|.:...:.|.|.:|::::..::|:.:||.||
 Worm   192 -------IRALDKDYCNGVFLYTLTHNSSRVGEFSCLLGMLKLKRAIGFHLVQSYIPTGLIVAIS 249

  Fly   316 WVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAF 380
            |||||:.....|||.:|..||||:..|........|..|||....:.::.||.:||||.|:|||.
 Worm   250 WVSFWIDRRAVPARVSLSFTTLLTLSTQGNGIRYALPAVSYAKAIDYFYGVCMLFIFGVLLEFAA 314

  Fly   381 VNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVIT 445
            ||:..||.|         ||       .|:.:..:..|
 Worm   315 VNSYMRRAN---------KY-------NHMAEKIQSAY--------------------------- 336

  Fly   446 IETPIIIGGS--LSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVF 508
                   ||.  ::..||     :.:|..|....:.:|......:..:.....:|.||:..||.|
 Worm   337 -------GGKPIIADYDS-----DYEEGPTKYYGNLNKNSAHLMYKALKFSRKALSIDKAARFAF 389

  Fly   509 PLSFIVFNALFW 520
            |..|.:||..:|
 Worm   390 PCVFAIFNVFYW 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	106/467 (23%)
lgc-42	NP_497489.3	Neur_chan_LBD	36..192	CDD:280998	27/168 (16%)
		Neur_chan_memb	239..401	CDD:280999	59/216 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910