Protein Alignment pHCl-2 and lgc-40

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_508428.2
• Gene: lgc-40 / 188854
• WormBaseID: WBGene00020767
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 118/495 - (23%)
• Similarity: 217/495 - (43%)
• Gaps: 82/495 - (16%)

  Fly    76 LTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLA 140
            |.:|.....|:|...|..:  ||  ||.::....:|..|.:..:..:.:.:....|..:.|.|||
 Worm    35 LDKLKNETLYNRFATPTQY--DG--VPTNVTLSMFIEGMSSFSAQTMDYHLDVYFQEEWYDHRLA 95

  Fly   141 FSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATL 205
            .::..|    .::.:..:.||:|.|.::..|.:::.....:..:.|..:||||.|....|:....
 Worm    96 HNASAP----ILVRDLTVFKMMWHPDVYFANARSAAFQDITDDNFLVWVYPNGRVWYDARISIVS 156

  Fly   206 YCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHW-ETDNPVSFDKQLQLTEYNLIGSLYNESIRV 269
            .|.|:..|:|.|.|:|...:.|:.|..|:::|.| |.::..:.|:...:|       :.:.|::.
 Worm   157 SCNMDLWKYPLDSQECALRILSYAYPMTVLRLLWSEKEDVPAIDRNPDIT-------MPDMSLKH 214

  Fly   270 SNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGC 334
            ....|.:.....|.:|.::....:.||:.::|:..::|:.:||.|||.:|||:.|..|||.:|..
 Worm   215 IRTGYCNGTYATGEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFNFWLEIDSAPARVSLSI 279

  Fly   335 TTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTK 399
            ||||:..|.:.:.:..|.:|||:...:||...|..|:||.::||    ||.....:|::
 Worm   280 TTLLTISTQANAVKLALPEVSYMKAIDVWMGSCMAFVFGVMIEF----TICHYAKNLEM------ 334

  Fly   400 YIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMD------------------------------ 434
              ::....|.|         ..|:.:||:...:.|
 Worm   335 --LRGDGQPSL---------IVDTALSTLFGAARDIDDLVRKVATLNEEEGVRGDGEQHIALNML 388

  Fly   435 -------KTCGPNNTVITIETPIIIGGS-LSREDSAISLD---EQDETSTSESSDSSKEKPAQTF 488
                   ::...||.|....|...:|.. :.|:.|..||.   :|..:....:.|.|:.....|.
 Worm   389 NPEEPRLRSLNQNNDVTANGTRYFVGAERMKRKRSKASLSRLRQQVASMRHATIDVSRRAFNWTR 453

  Fly   489 A--TMTPKEVSLWIDRKMRFVFPLSFIVFNALFWT--LVY 524
            |  .:..:.|:..||.:.|.|||:.|::||..:|:  ||:
 Worm   454 ALRNLRGRRVAQRIDERCRIVFPMIFLLFNVAYWSFYLVF 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	116/491 (24%)
lgc-40	NP_508428.2	LIC	9..490	CDD:273305	116/490 (24%)
		Neur_chan_LBD	44..242	CDD:280998	47/212 (22%)
		Neur_chan_memb	249..487	CDD:280999	64/258 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910