Protein Alignment pHCl-2 and lgc-50

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_498637.3
• Gene: lgc-50 / 188633
• WormBaseID: WBGene00020605
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 119/498 - (23%)
• Similarity: 228/498 - (45%)
• Gaps: 58/498 - (11%)

  Fly    56 STVNNCPSLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSS 120
            :...|.|...:..|:.|.:|:..|...  ||..:.|   ..:|..|.:::    ::..:..:...
 Worm    16 AATTNSPKKCSRNSINLGKLIDTLLTD--YDTHLLP---EAEGVNVTIEL----HVQGVSGISEI 71

  Fly   121 DLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDE 185
            ...|::..:....:.||||:| .:|......|..:|:.:|.:|.|...:.|.::|::..:.:::.
 Worm    72 TGDFSLDVMYSEIWQDPRLSF-KHLNVCATNITLKSDFRKKIWTPDTCIINSKSSSIHSSPSENT 135

  Fly   186 LTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQ 250
            ...:|.||.|.::.||.....|.:|.:.||||...|:..|||:.:||..|:|.|. |.|::..::
 Worm   136 FVILYENGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEVRLMWH-DVPITMMEK 199

  Fly   251 LQLTEYNLIG-SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTI 314
            ::|.:::||| |..::.:...|..:        :.:.:.||  ..|..|:|:...:.|:.:.|..
 Worm   200 VELPDFDLIGWSTDHQRLEYPNGIW--------DRAKVKFT--FARRYGFYLFQSYFPTSLTVIS 254

  Fly   315 SWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFA 379
            |||.|:.......||.|||.::||:......:...:|.:|||:...:||.:...||||.:|||.|
 Worm   255 SWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLDVWMIFSVIFIFCTLVELA 319

  Fly   380 FVNTI--WRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHG--------------YRRTDSTMSTM 428
            .|..:  |.|...:..|       |...::..::|.|:..              .|:....::.:
 Worm   320 IVCQLNRWERERQIGSK-------VLGHWLNQIRKTRKKESKADEGGGGGVGGLLRKRIPVLAQL 377

  Fly   429 STTSMDKTCGPNNTVIT-IETPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPA-----QT 487
            ...:.|...|....:.| |:.|.....|::..|:: .|...:.||....:.:.::|..     |.
 Worm   378 KAAATDSNSGAATAMTTAIQPPNTNLNSITNSDNS-KLVANNFTSIEHETYAYEKKRGFSHCFQR 441

  Fly   488 FA-TMTPKE-----VSLWIDRKMRFVFPLSFIVFNALFWTLVY 524
            |. .:.|.:     .|:.:||....:|||||::||.::|::.:
 Worm   442 FVYAICPPDRDWTITSVQVDRCSMIMFPLSFLIFNVVYWSIYF 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	119/494 (24%)
lgc-50	NP_498637.3	LIC	34..483	CDD:273305	115/477 (24%)
		Neur_chan_LBD	34..237	CDD:280998	53/223 (24%)
		Neur_chan_memb	245..480	CDD:280999	59/242 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810