Protein Alignment pHCl-2 and glc-4

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_495489.2
• Gene: glc-4 / 182971
• WormBaseID: WBGene00001594
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 128/534 - (23%)
• Similarity: 208/534 - (38%)
• Gaps: 112/534 - (20%)

  Fly    46 AFSVSINLSQSTVNNCPSLKNA----------ESMALMELLTRLTAPCRYDRMVPPVVHNKDGEE 100
            |..||....:|...:|.....:          |.|.:.:||.      .||..|.|     .|..
 Worm    12 ALLVSSTAKKSKTKSCKRTAFSRHTTNYQAWREQMTVCDLLQ------DYDAAVRP-----SGRT 65

  Fly   101 VPMDIYARFYIYVMKNLDS------SDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK 159
            ...|......:....|:.|      .:::|..|...:..:.|.||.|..:     |.:: .|:.:
 Worm    66 PYNDTRGAVMVTTSLNIRSISAVSEKNMEFVAQFRFRQEWYDDRLRFIEH-----QGLL-SSDYR 124

  Fly   160 ----------KMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKF 214
                      :.||:|..|..||:.......:.::....|..:|.::...||...|.|.|:..::
 Worm   125 NFEFIHVARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSDGKLIYDRRLTLHLACSMHLSRY 189

  Fly   215 PFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGS 279
            |.|.|.|:....|:.|.|..::..|  |.|.     :|:.| ...|:|.|..|.....:..:..:
 Worm   190 PMDHQNCEIAFASYAYTTADIEYIW--DVPA-----IQIHE-GANGALPNFEIASFKNASCTSKT 246

  Fly   280 LEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLS 344
            ..|.||.:...:.|.|...::::..::||.|:|.::|||:|:....|.||..|...|||:.||.|
 Worm   247 NTGTYSCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMITTS 311

  Fly   345 LSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKK------RTTKYIVK 403
            .:..:||..|||....::|...|.:|||.||:|:|.||.:...:...|:||      |.:..|..
 Worm   312 HAINSNLPPVSYAKSIDIWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKKAACNRSRLSNVIEN 376

  Fly   404 S---------TFVPHLKKH--RRHGYRRTDSTMSTMSTTSM-DKTCGPNNTVITIE--------T 448
            .         ||.|..||.  ||...:..:..........| |:  ||..:...:|        |
 Worm   377 DNFGESLQSLTFSPQEKKRLIRRRPKKNMEMQEGDFEAIEMVDR--GPPRSAGLMEEGWTFHDTT 439

  Fly   449 PIIIGGSLSRED-----SAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVF 508
            .::..|...|.:     |.:            ||....|:                ||...|.:|
 Worm   440 DLVYIGQRKRVELVRWCSVL------------SSRGRAER----------------IDIIARIIF 476

  Fly   509 PLSFIVFNALFWTL 522
            ||:||:||..:|::
 Worm   477 PLAFILFNFAYWSI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	128/532 (24%)
glc-4	NP_495489.2	LIC	26..491	CDD:455710	124/520 (24%)