Protein Alignment pHCl-2 and lgc-55

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_507870.2
• Gene: lgc-55 / 180312
• WormBaseID: WBGene00013746
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 131/529 - (24%)
• Similarity: 233/529 - (44%)
• Gaps: 90/529 - (17%)

  Fly    32 ANGSVVVSPLNTTDAFSVSINLSQSTVNNCP--SLKNAESMALMELLTRLTAPCRYDRMVPPVVH 94
            :|||..:    .:|.....:.|||.:..:.|  .|..||. |...:||.|.:  :|||.:.|.:.
 Worm    51 SNGSCAM----VSDLARGGLGLSQDSEEDEPFCVLGQAEK-AATRILTELLS--KYDRNLVPKMK 108

  Fly    95 NKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAF-----SSYLPNRRQPIMG 154
            .       :|:.....|..:..:.......|:..|....:.||.|:|     :..|.|    :..
 Worm   109 G-------VDVDVELLIQRVSEISEIQSSSTMHILFSQIWHDPGLSFEHEEGAHCLTN----LSL 162

  Fly   155 ESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQ 219
            ...:...:|:|::.:.|.:.|.:..:...:...:|:|||||..:.|:.....|.|:|..||.|..
 Worm   163 SHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYRVVVESPCEMDFSFFPMDRV 227

  Fly   220 KCKTTLESWMYNTTLVQLHWETD-NPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGN 283
            .|.|..||:.:|...|:|||:.. .||.|...::|.::::...::.::..:    |.:     |.
 Worm   228 MCTTIFESYAFNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFI----YPA-----GV 283

  Fly   284 YSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQ- 347
            :..::..:|..|..|:|::..:||:..:|.|||:||||.....|||.|||.::|:: :||..|.
 Worm   284 WDQLNIKLLFRRSYGFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMA-LTLQYSNV 347

  Fly   348 ENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFV--PHL 410
            ..:|.|||||...:::...|.::||.|:||.|.|.::.:|.     ::||.   ....|:  ..:
 Worm   348 SRSLPKVSYVKGLDLFMFGCIVYIFLSIVELAVVGSLEQRK-----QQRTN---ADGDFLSDDDI 404

  Fly   411 KKHRRHGYRRTDSTMSTMS-----TTSMDKTCGPNNTVITIETPIIIGGSLSR------EDSAIS 464
            ||:.   ::||.||.|..|     .....:...|.:           ||...:      |.:.:.
 Worm   405 KKNI---FQRTFSTKSFKSGYGARHHQFSECASPED-----------GGEWPKTRTEWAERTYVE 455

  Fly   465 LDEQDETSTS---ESSDSSKEK----PAQTFAT-------MTPKEVSLW----IDRKMRFVFPLS 511
            ..|.:...::   |..:.|..|    ..|..|:       |:.|....|    :||..:.:||::
 Worm   456 CPEPEPPESNRHPEVENDSNNKMLVLVRQRRASRKRRKRLMSGKLFQRWTAEDMDRFCQKLFPIT 520

  Fly   512 FIVFNALFW 520
            |...|.::|
 Worm   521 FTFCNLIYW 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	127/515 (25%)
lgc-55	NP_507870.2	Neur_chan_LBD	88..295	CDD:280998	50/228 (22%)
		LIC	90..532	CDD:273305	119/485 (25%)
		Neur_chan_memb	304..>391	CDD:280999	35/92 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810