Protein Alignment pHCl-2 and lgc-49

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_505841.2
• Gene: lgc-49 / 179547
• WormBaseID: WBGene00010741
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 450
• Identity: 114/450 - (25%)
• Similarity: 194/450 - (43%)
• Gaps: 71/450 - (15%)

  Fly    82 PCRYDRMVPPVVHNK----DGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFS 142
            |...|:::....:||    :...||:.:  .|::..:.:::.....|.:...:...:|||.|.|
 Worm    55 PAIIDKLLNGTGYNKFRIPNENGVPVQV--EFWVQAITSINEITNDFEMDIYINEMWLDPALKF- 116

  Fly   143 SYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYC 207
            .:|...:|.:....::.:.||.|:....|.:.:.:..:..|:....|||||||..:.|:.....|
 Worm   117 DHLNPCKQNLSVSHQVLEQLWTPNSCFVNSKFAEIHDSPFKNVFLMIYPNGTVWVNYRVNVKGPC 181

  Fly   208 WMNFQKFPFDEQKCKTTLESWMYNTTLVQLHW--ETDNPVSFDKQLQLTEYNLIGSLYNESIRVS 270
            .::.:.||.|.|:|....||:.||...|::.|  ::..|||...:::|.::.||..   ||.|:|
 Worm   182 DLSLELFPLDIQECHLIYESFNYNNQEVRMRWNEKSAEPVSVTNKIRLPDFELIKI---ESTRIS 243

  Fly   271 NESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCT 335
             ..|.:     |.:..:...::..|...:|.:..:||:.:.:.|||:||.|.....||||.||..
 Worm   244 -APYPA-----GMWDELHVKLVFERRYIWYFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVN 302

  Fly   336 TLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKY 400
            .||:.|....:...||.:||||...:||.||...|||.||:|.|.|.  ::..|:...||:
 Worm   303 ALLAMIFQFGNIMRNLPRVSYVKAIDVWMLVSMTFIFLSLLELAIVG--YKTKNEEGSKKK---- 361

  Fly   401 IVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDK-TCGPNNTVITIETPIIIGGSLSREDSAIS 464
                  .||.|                    .:|. ...|              ..|.|.:....
 Worm   362 ------CPHKK--------------------LLDNFEASP--------------AGLCRYEKRFM 386

  Fly   465 LDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTLVY 524
            |..  |..::......:.:..|.|...:|::    |||....:||..|.:||.::|:..|
 Worm   387 LPV--ERRSARWGGIIRFQVFQDFWNWSPEK----IDRVSAIMFPACFAIFNIVYWSYYY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	113/446 (25%)
lgc-49	NP_505841.2	LIC	53..439	CDD:273305	113/447 (25%)
		Neur_chan_LBD	57..264	CDD:280998	52/218 (24%)
		Neur_chan_memb	272..436	CDD:280999	58/215 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810