Protein Alignment pHCl-2 and lgc-37

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 125/487 - (25%)
• Similarity: 217/487 - (44%)
• Gaps: 76/487 - (15%)

  Fly    54 SQSTVNNCPSLKNAESMALMELLTRL--TAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKN 116
            |:||..|         ..|:...|::  |.....|:...||  |.|..  |:.:.....|..|..
 Worm    31 SRSTTYN---------QTLIRYTTKVLDTILLNQDKNFRPV--NPDNS--PLQVEVDISIRSMGP 82

  Fly   117 LDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQ-PIMGESELKKMLWVPHIFLTNEQASTVLGT 180
            :...:::|::....:.::||.||||:...|::.: |:  .|::.|.:|:|..::.|.:.|.:...
 Worm    83 VSEQNMEFSLDCYFRQKWLDRRLAFTPINPSKPEIPL--ASKMLKDIWIPDTYIRNGRKSYLHTL 145

  Fly   181 SAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPV 245
            :..:.|..:..:|.|..|.||.....|.|..:|||.|.|.|...:.|..|.:..|...|:   .|
 Worm   146 TVPNILFRVRSDGQVHVSQRLTIRSRCQMFLKKFPMDTQACPIEVGSLGYFSKDVVYKWK---DV 207

  Fly   246 SFDKQL--QLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPS 308
            ..|.::  .|::|.:: ||......||:..:.     :.|.|:::....|.|:.|||::..:.|.
 Worm   208 ELDAKMGNTLSQYQVL-SLSKSERNVSDFRFS-----DRNISVLNVYFKLQRQQGYYILQIYTPC 266

  Fly   309 IMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFG 373
            .::|.:||||||:..:.:|||.:||..|:||..|:......:|.|||:.|..:|:.|.|.:|:|.
 Worm   267 TLVVVMSWVSFWINKEASPARVSLGIMTVLSMSTIGFGLRTDLPKVSHSTALDVYILTCFVFLFA 331

  Fly   374 SLVEFAFVN-----TIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSM 433
            ::||:|.:|     .|.::.:||       |.:.::|.:..:......|.||.|       |..:
 Worm   332 AMVEYAVINYAQIVYIRKQIHDL-------KGLEQNTAMGQMFTAGLMGARRRD-------TIQV 382

  Fly   434 DKTCGPNNTVITIETPIIIGGSLSREDSAISL----------DEQDETSTSESSDSSKEKPAQTF 488
            |.        :|:|          :|::.:..          |||..||.............:|.
 Worm   383 DD--------LTVE----------KEEARLKAVPWWKKLCFKDEQGNTSMFYRMAVKAAIAKKTL 429

  Fly   489 ATMTPKEVSLWIDRKMRFVFPLSFIVFNALFW 520
            ....|.||...||...:..||..:|:||..:|
 Worm   430 RNGDPAEVVNKIDNFSKLAFPTLYIIFNVFYW 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	125/487 (26%)
lgc-37	NP_499662.2	LIC	44..464	CDD:455710	120/465 (26%)
		LGIC_ECD	68..254	CDD:475126	47/196 (24%)