Protein Alignment pHCl-2 and Glra4

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_034427.2
• Gene: Glra4 / 14657
• MGIID: 95750
• Length: 456
• Species: Mus musculus
• Alignment Length: 482
• Identity: 134/482 - (27%)
• Similarity: 223/482 - (46%)
• Gaps: 65/482 - (13%)

  Fly    49 VSINLSQSTVNNCPSLKNAESMALMELLTRLTA-PCRYDRMVPPVVHNKDGEEVPMDIYARFYIY 112
            :|:.|::..|.:  .||.::.|:..:.|.:|.. ...||..:.|   |..|.  |:::....:|.
Mouse    22 LSVALAKEDVKS--GLKGSQPMSPSDFLDKLMGRTSGYDARIRP---NFKGP--PVNVTCNIFIN 79

  Fly   113 VMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRR---QPIMGESELKKMLWVPHIFLTNEQA 174
            ...::..:.:.:.|...|:.::.|||||:..| |:..   .|.|.:|     :|.|.:|..||:.
Mouse    80 SFGSVTETTMDYRVNVFLRQQWNDPRLAYREY-PDDSLDLDPSMLDS-----IWKPDLFFANEKG 138

  Fly   175 STVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHW 239
            :.....:..::|..|:.||.||.|.||...|.|.|:.:.||.|.|.|...|||:.|....:...|
Mouse   139 ANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEW 203

  Fly   240 ETDNP-VSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVID 303
            ..|.| |...:.|.|.::.|...        .:..|.:.....|.::.|.....|.|::|||:|.
Mouse   204 LEDAPAVQVAEGLTLPQFILRDE--------KDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQ 260

  Fly   304 YFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCT 368
            .::||::||.:||||||:..|..|||..||.||:|:..|.|.....:|.|||||...::|..||.
Mouse   261 MYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCL 325

  Fly   369 IFIFGSLVEFAFVNTIWRRNND-LQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTS 432
            :|:|.:|:|:|.||.:.|::.: ::|::|..:..::...:...:.:.| ||        .:....
Mouse   326 LFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRESRFYFR-GY--------GLGHCL 381

  Fly   433 MDKTCGPNNTVITIETPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVS 497
            ..:..||           :.|.|:........|.::.||......|.:|.
Mouse   382 QARDGGP-----------MEGSSIYSPQPPTPLLKEGETMRKLYVDRAKR--------------- 420

  Fly   498 LWIDRKMRFVFPLSFIVFNALFWTLVY 524
              ||...|.|||.:|:|||..:| :||
Mouse   421 --IDTISRAVFPFTFLVFNIFYW-VVY 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	132/478 (28%)
Glra4	NP_034427.2	LIC	9..444	CDD:273305	132/480 (28%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	236..241		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910