Protein Alignment pHCl-2 and Glra1

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001277750.1
• Gene: Glra1 / 14654
• MGIID: 95747
• Length: 457
• Species: Mus musculus
• Alignment Length: 484
• Identity: 132/484 - (27%)
• Similarity: 223/484 - (46%)
• Gaps: 61/484 - (12%)

  Fly    47 FSVSINLSQSTVNNCPSLKNAESMALMELLTRLTA-PCRYDRMVPPVVHNKDGEEVPMDIYARFY 110
            ||::.:.......:.|     :.|:..:.|.:|.. ...||..:.|   |..|.  |:::....:
Mouse    18 FSLAASKEAEAARSAP-----KPMSPSDFLDKLMGRTSGYDARIRP---NFKGP--PVNVSCNIF 72

  Fly   111 IYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRR---QPIMGESELKKMLWVPHIFLTNE 172
            |....::..:.:.:.|...|:.::.|||||::.| |:..   .|.|.:|     :|.|.:|..||
Mouse    73 INSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEY-PDDSLDLDPSMLDS-----IWKPDLFFANE 131

  Fly   173 QASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQL 237
            :.:.....:..::|..|..||.||.|.|:..||.|.|:.:.||.|.|.|...|||:.|....:..
Mouse   132 KGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196

  Fly   238 HWETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVI 302
            .|:....|.....|.|.::.|   ...:.:|...:.|.:     |.::.|.....|.|::|||:|
Mouse   197 EWQEQGAVQVADGLTLPQFIL---KEEKDLRYCTKHYNT-----GKFTCIEARFHLERQMGYYLI 253

  Fly   303 DYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVC 367
            ..::||::||.:||:|||:..|..|||..||.||:|:..|.|.....:|.|||||...::|..||
Mouse   254 QMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVC 318

  Fly   368 TIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTS 432
            .:|:|.:|:|:|.||.:.|::.:| |:.|..:...||..: :|.:....|..|.:     .|...
Mouse   319 LLFVFSALLEYAAVNFVSRQHKEL-LRFRRKRRHHKSPML-NLFQDDEGGEGRFN-----FSAYG 376

  Fly   433 MDKTCGPNNTVITIETPIIIGGSLSRED--SAISLDEQDETSTSESSDSSKEKPAQTFATMTPKE 495
            |...|                  |..:|  |....:..:.|:...:...|.|:..:.|.....|
Mouse   377 MGPAC------------------LQAKDGISVKGANNNNTTNPPPAPSKSPEEMRKLFIQRAKK- 422

  Fly   496 VSLWIDRKMRFVFPLSFIVFNALFWTLVY 524
                ||:..|..||::|::||..:| ::|
Mouse   423 ----IDKISRIGFPMAFLIFNMFYW-IIY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	131/480 (27%)
Glra1	NP_001277750.1	LIC	7..446	CDD:273305	131/482 (27%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	230..235		2/9 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..410		2/18 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910