DRSC/TRiP Functional Genomics Resources

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Protein Alignment pHCl-2 and Gabrr1

DIOPT Version :9

Sequence 1:NP_001303470.1 Gene:pHCl-2 / 43703 FlyBaseID:FBgn0039840 Length:526 Species:Drosophila melanogaster
Sequence 2:NP_032101.3 Gene:Gabrr1 / 14408 MGIID:95625 Length:480 Species:Mus musculus


Alignment Length:438 Identity:102/438 - (23%)
Similarity:205/438 - (46%) Gaps:67/438 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 GEEVPMDIYARFYIYVMKNLDS---SDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELK 159
            |..:|:.:..:     :::|||   .|:.||:...|:..:.|.||:|.|   :....:..:..|.
Mouse    95 GPAIPVGVDVQ-----VESLDSISEVDMDFTMTLYLRHYWKDERLSFPS---SNNLSMTFDGRLV 151

  Fly   160 KMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTT 224
            |.:|||.:|..:.:.|.:..|:..:.:..:.|:|.||.|.|:..|..|.|:|.:||.|.|.|...
Mouse   152 KKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLE 216

  Fly   225 LESWMYNTTLVQLHWETDN-PVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIIS 288
            :||:.|....:.|:|:..| .:..|:::.|::: ||...:       ..:.::..|..|.|:.:.
Mouse   217 IESYAYTEDDLMLYWKKGNDSLKTDERISLSQF-LIQEFH-------TTTKLAFYSSTGWYNRLY 273

  Fly   289 FTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMK 353
            ....|.|.:.::::..:.|:.::|.:||||||:.....|||..||.||:|:..|:......::.:
Mouse   274 INFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPR 338

  Fly   354 VSYVTMSEVWFLVCTIFIFGSLVEFAFVN--TIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRH 416
            |||:...:::..|..:|:|.|::|:|.||  |..:...:.:|:::                    
Mouse   339 VSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREK-------------------- 383

  Fly   417 GYRRTDSTMSTMSTTSMDKTCG-PNNTVITIETPII------IGGSLSREDSAISLDEQDETSTS 474
                            :..||| |....:.:::...      :||.:  .::....|......|.
Mouse   384 ----------------ISCTCGLPQPRGVMLDSSYSDGEVNDLGGYM--PENGEKPDRMMVQLTL 430

  Fly   475 ESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTL 522
            .|...|.::..|..:.::.:..:..||:..|.:||.::|:||.::|::
Mouse   431 ASERGSPQRKGQRGSYVSMRINTHAIDKYSRIIFPAAYILFNLIYWSI 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pHCl-2NP_001303470.1 LIC 46..522 CDD:273305 102/436 (23%)
Gabrr1NP_032101.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 29..67
LIC 76..479 CDD:273305 102/438 (23%)
Neur_chan_LBD 77..282 CDD:280998 52/202 (26%)
Neur_chan_memb 289..476 CDD:280999 49/224 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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