Protein Alignment pHCl-2 and Gabrg3

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_017177467.1
• Gene: Gabrg3 / 14407
• MGIID: 95624
• Length: 468
• Species: Mus musculus
• Alignment Length: 473
• Identity: 115/473 - (24%)
• Similarity: 214/473 - (45%)
• Gaps: 64/473 - (13%)

  Fly    62 PSLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTV 126
            |..::.:...::..|.|     .||:.:.|.:..|     |..|....|:..:..:.|.::::.:
Mouse    40 PKSQDTDVTLILNKLLR-----EYDKKLRPDIGIK-----PTVIDVDIYVNSIGPVSSINMEYQI 94

  Fly   127 QGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYP 191
            .......:.|.||.|:|.:    :.:...|.:..::|:|.....|.:.:.....:..::|..|:.
Mouse    95 DIFFAQTWTDSRLRFNSTM----KILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWN 155

  Fly   192 NGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFD-KQLQLTE 255
            :|.:|.:.||.....|.:....||.|...|..|..|:.|....:...|..::..:.| |..:|.:
Mouse   156 DGKILYTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQ 220

  Fly   256 YNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFW 320
            ::.:| |.|.:..|:..:        |:|.:::....|:|.:||:.|..::|.|:.|.:||||||
Mouse   221 FDFMG-LRNTTEIVTTSA--------GDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFW 276

  Fly   321 LQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIW 385
            ::.|.||||||||.||:|:..|||.....:|.:|||||..:::..||.:|:|.:|:|:|.:|
Mouse   277 IKKDATPARTTLGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLN--- 338

  Fly   386 RRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNN-TVITIETP 449
                           ...|...|.::|.:.......|||.......|:.   .|:| :::.:..|
Mouse   339 ---------------YYSSCRKPTIRKKKTSQLLHPDSTRWIPDRISLQ---APSNYSLLDMRPP 385

  Fly   450 IIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPK-EVSLW-----------IDR 502
            ..:..:|   ::::...|.::|...|..|.   |..|:|.....: :...|           :|.
Mouse   386 PPVMITL---NNSMYWQEFEDTCVYECLDG---KDCQSFFCCYEECKSGSWRRGRIHIDVSELDS 444

  Fly   503 KMRFVFPLSFIVFNALFW 520
            ..|..||.||::||.::|
Mouse   445 YSRVFFPTSFLLFNLVYW 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	115/473 (24%)
Gabrg3	XP_017177467.1	LIC	50..465	CDD:273305	114/463 (25%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	37/193 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900