Protein Alignment pHCl-2 and Gabrg1

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Alignment Length: 537
• Identity: 126/537 - (23%)
• Similarity: 222/537 - (41%)
• Gaps: 123/537 - (22%)

  Fly     6 IFVLISYLGLSSAAGVHLGDL--------QQNLAANGSVVVSP-LNTTDAFSVSINLSQSTVNNC 61
            ||:|::         :|||:.        .::|..|.:.|::| ::..|...:..:|.|.
Mouse    24 IFLLLT---------LHLGNCVDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQG----- 74

  Fly    62 PSLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTV 126
                                   ||..:.|.:..:     |..|....|:..:..:|..::::|:
Mouse    75 -----------------------YDNKLRPDIGVR-----PTVIETDVYVNSIGPVDPINMEYTI 111

  Fly   127 QGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYP 191
            ..:....:.|.||.|:|.:    :.:|..|.:...:|:|..|..|.:.|.....:..:.|..|:.
Mouse   112 DIIFAQTWFDSRLKFNSTM----KVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWS 172

  Fly   192 NGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDN-PVSFDKQLQLTE 255
            :|.||.:.||.....|::....||.||..|.....|:.|....::..|:..: .|:..|..:|.:
Mouse   173 DGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQ 237

  Fly   256 YNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFW 320
            :..:|        :.|.:.:|| ::.|:|.|::....|:|.:||:.|..::|.|:.|.:||||||
Mouse   238 FAFVG--------LRNSTEISH-TISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFW 293

  Fly   321 LQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIW 385
            :..|..||||:||.||:|:..|||.....:|.||||||..:::..||.||:|.:|:|:..::...
Mouse   294 INKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFT 358

  Fly   386 RRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPI 450
            ..|.....:.|..|.  |::..|.|         ...||:..|::.|:.:
Mouse   359 SNNKGKTTRGRKLKN--KTSASPGL---------HAGSTLIPMNSISLPQ--------------- 397

  Fly   451 IIGGSLSREDSAIS-LDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLW-----------IDRK 503
                  ..:|.... |:.:|.||              .|..........|           ||..
Mouse   398 ------GEDDYGYQCLEGKDCTS--------------FFCCFDDCRTGSWREGRIHIRIAKIDSY 442

  Fly   504 MRFVFPLSFIVFNALFW 520
            .|..||.:|.:||.::|
Mouse   443 SRIFFPTAFALFNLVYW 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	115/488 (24%)
Gabrg1	NP_034382.2	Neur_chan_LBD	65..270	CDD:280998	50/250 (20%)
		LIC	66..462	CDD:273305	115/486 (24%)
		Neur_chan_memb	277..459	CDD:280999	61/227 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810