Protein Alignment pHCl-2 and Gabra6

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_036012221.1
• Gene: Gabra6 / 14399
• MGIID: 95618
• Length: 459
• Species: Mus musculus
• Alignment Length: 347
• Identity: 101/347 - (29%)
• Similarity: 158/347 - (45%)
• Gaps: 51/347 - (14%)

  Fly   100 EVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKM--- 161
            ||..|||...:    ..:...::::|:....:..:.|.||.|.           |.:|:..:
Mouse    57 EVKTDIYVTSF----GPVSDVEMEYTMDVFFRQTWTDERLKFK-----------GPAEILSLNNL 106

  Fly   162 ----LWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCK 222
                :|.|..|..|.:.|.....:..::|..:..|||:|.:.||.....|.|....||.|...|.
Mouse   107 MVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACP 171

  Fly   223 TTLESWMYNTTLVQLHWETDNPVSF---DKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNY 284
            ....|:.|..|.:...|:.....|.   ::...|.:|:|||.      .||:|:..|:   .|.|
Mouse   172 LKFGSYAYPKTEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQ------TVSSETIKSN---TGEY 227

  Fly   285 SIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQEN 349
            .|::....|.|::||::|..:.|.||.|.:|.||||:..:..||||..|.||:|:..|||:|..:
Mouse   228 VIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARH 292

  Fly   350 NLMKVSYVTMSEVWFL-VCTIFIFGSLVEFAFVN---TIWRRNNDLQLKKRTTKYIVKS------ 404
            :|.||||.|..: ||: ||..|:|.:|:|||.||   .:..:..:.|.:...|..:.||
Mouse   293 SLPKVSYATAMD-WFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAATPPVAKSKASESL 356

  Fly   405 ------TFVPHLKKHRRHGYRR 420
                  |..|..::.||...||
Mouse   357 QAEIVVTAPPQKRRRRRRRRRR 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	101/347 (29%)
Gabra6	XP_036012221.1	LGIC_ECD_GABAAR_A6	42..239	CDD:349840	48/205 (23%)
		LGIC_TM_GABAAR_alpha	242..337	CDD:349854	41/95 (43%)
		TM1 helix	245..265	CDD:349854	10/19 (53%)
		TM2 helix	274..295	CDD:349854	8/20 (40%)
		TM3 helix	305..327	CDD:349854	12/21 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900